HIV-1 Tat interacts with cyclin T1 to direct the P-TEFb CTD kinase complex to TAR RNA

被引:73
|
作者
Garber, ME [1 ]
Wei, P [1 ]
Jones, KA [1 ]
机构
[1] Salk Inst Biol Studies, Regulatory Biol Lab, La Jolla, CA 92037 USA
关键词
D O I
10.1101/sqb.1998.63.371
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:371 / 380
页数:10
相关论文
共 50 条
  • [11] A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat
    Verstraete, Nina
    Kuzmina, Alona
    Diribarne, Gaelle
    Nguyen, Van Trung
    Kobbi, Lydia
    Ludanyi, Monika
    Taube, Ran
    Bensaude, Olivier
    RETROVIROLOGY, 2014, 11
  • [12] A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat
    Nina Verstraete
    Alona Kuzmina
    Gaelle Diribarne
    Van Trung Nguyen
    Lydia Kobbi
    Monika Ludanyi
    Ran Taube
    Olivier Bensaude
    Retrovirology, 11
  • [13] The chaperone protein p32 stabilizes HIV-1 Tat and strengthens the p-TEFb/RNAPII/TAR complex promoting HIV transcription elongation
    Li, Chuan
    Mori, Luisa P.
    Lyu, Shuang
    Bronson, Ronald
    Getzler, Adam J.
    Pipkin, Matthew E.
    Valente, Susana T.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 120 (01)
  • [14] Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex
    Schulze-Gahmen, Ursula
    Echeverria, Ignacia
    Stjepanovic, Goran
    Bai, Yun
    Lu, Huasong
    Schneidman-Duhovny, Dina
    Doudna, Jennifer A.
    Zhou, Qiang
    Sali, Andrej
    Hurley, James H.
    ELIFE, 2016, 5
  • [15] Controlling Cellular P-TEFb Activity by the HIV-1 Transcriptional Transactivator Tat
    Muniz, Lisa
    Egloff, Sylvain
    Ughy, Bettina
    Jady, Beata E.
    Kiss, Tamas
    PLOS PATHOGENS, 2010, 6 (10)
  • [16] Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR
    Sedore, Stanley C.
    Byers, Sarah A.
    Biglione, Sebastian
    Price, Jason P.
    Maury, Wendy J.
    Price, David H.
    NUCLEIC ACIDS RESEARCH, 2007, 35 (13) : 4347 - 4358
  • [17] Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb
    Huang, Fang
    Nguyen, Trang T. T.
    Echeverria, Ignacia
    Ramachandran, Rakesh
    Cary, Daniele C.
    Paculova, Hana
    Sali, Andrej
    Weiss, Arthur
    Peterlin, Boris Matija
    Fujinaga, Koh
    ELIFE, 2021, 10
  • [18] Flavopiridol binding to P-TEFb (CDK9/cyclin T1)
    Johnson, Louise N.
    Baumli, Sonja
    Lolli, Graziano
    Lowe, Ed
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 : C122 - C122
  • [19] Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro
    Zhu, YR
    Peery, T
    Peng, TM
    Ramanathan, Y
    Marshall, N
    Marshall, T
    Amendt, B
    Mathews, MB
    Price, DH
    GENES & DEVELOPMENT, 1997, 11 (20) : 2622 - 2632
  • [20] An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb
    Shortridge, Matthew D.
    Wille, Paul T.
    Jones, Alisha N.
    Davidson, Amy
    Bogdanovic, Jasmina
    Arts, Eric
    Karn, Jonathan
    Robinson, John A.
    Varani, Gabriele
    NUCLEIC ACIDS RESEARCH, 2019, 47 (03) : 1523 - 1531