Zwitterionic-Type Molten Salt-Catalyzed Multicomponent Reactions: One-Pot Synthesis of Substituted Imidazoles Under Solvent-Free Conditions

被引：17

作者：

Bagdi, Matiur Rahman Avik Kr. ^{[1
]}

Kundu, Dhiman ^{[1
]}

Majee, Adinath ^{[1
]}

Hajra, Alakananda ^{[1
]}

机构：

[1] Visva Bharati Univ, Dept Chem, Santini Ketan 731235, W Bengal, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2012年 / 49卷 / 05期

关键词：

MICROWAVE IRRADIATION; 1,2,4,5-TETRASUBSTITUTED IMIDAZOLES; REUSABLE CATALYST; IONIC LIQUID; EFFICIENT; MILD; 1,2-DIKETONES; DERIVATIVES; ALDEHYDES;

D O I：

10.1002/jhet.924

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-(1-Imidazolium) butane sulfonate is an excellent catalyst for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles through the condensation of 1,2-dicarbonyl compounds, aldehydes, and ammonium acetate or amine via multicomponent condensation strategy under solvent-free conditions. The key advantages of this process are high yields, reusability of catalyst, environmental friendliness, easy work-up and purification of products by nonchromatographic methods.

引用

页码：1224 / 1228

页数：5

共 31 条

[1] One-pot synthesis of tetrasubstituted imidazoles catalyzed by zeolite HY and silica gel under microwave irradiation [J].

Balalaie, S ;

Arabanian, A .

GREEN CHEMISTRY, 2000, 2 (06) :274-276

[2] On Catalysis by Ionic Liquids [J].

Chakraborti, Asit K. ;

Roy, Sudipta Raha .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (20) :6902-+

[3] Substituted imidazoles as glucagon receptor antagonists [J].

Chang, LL ;

Sidler, KL ;

Cascieri, MA ;

de Laszlo, S ;

Koch, G ;

Li, B ;

MacCoss, M ;

Mantlo, N ;

O'Keefe, S ;

Pang, M ;

Rolando, A ;

Hagmann, WK .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (18) :2549-2553

[4] Reactivity of ionic liquids [J].

Chowdhury, Shahana ;

Mohan, Ram S. ;

Scott, Janet L. .

TETRAHEDRON, 2007, 63 (11) :2363-2389

[5] Green, One-Pot, Solvent-Free Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Using a BrOnsted Acidic Ionic Liquid as Novel and Reusable Catalyst [J].

Davoodnia, Abolghasem ;

Heravi, Majid M. ;

Safavi-Rad, Zahra ;

Tavakoli-Hoseini, Niloofar .

SYNTHETIC COMMUNICATIONS, 2010, 40 (17) :2588-2597

[6] Recent developments in isocyanide based multicomponent reactions in applied chemistry [J].

Dömling, A .

CHEMICAL REVIEWS, 2006, 106 (01) :17-89

[7]

Dömling A, 2000, ANGEW CHEM INT EDIT, V39, P3168, DOI 10.1002/1521-3773(20000915)39:18<3168::AID-ANIE3168>3.0.CO

[8]

2-U

[9] ANTI-MYCOTIC IMIDAZOLES .4. SYNTHESIS AND ANTIFUNGAL ACTIVITY OF KETOCONAZOLE, A NEW POTENT ORALLY ACTIVE BROAD-SPECTRUM ANTIFUNGAL AGENT [J].

HEERES, J ;

BACKX, LJJ ;

MOSTMANS, JH ;

VANCUTSEM, J .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (08) :1003-1005

[10] Biocatalysis in supercritical fluids, in fluorous solvents, and under solvent-free conditions [J].

Hobbs, Helen R. ;

Thomas, Neil R. .

CHEMICAL REVIEWS, 2007, 107 (06) :2786-2820

← 1 2 3 4 →