Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging

被引：368

作者：

Li, Yantao ^{[1
]}

Tang, Jinglong ^{[1
]}

He, Liangcan ^{[1
]}

Liu, Yong ^{[1
]}

Liu, Yaling ^{[1
]}

Chen, Chunying ^{[1
]}

Tang, Zhiyong ^{[1
]}

机构：

[1] Chinese Acad Sci, Natl Ctr Nanosci & Technol, Key Lab Nanosyst & Hierarch Fabricat, Beijing 100190, Peoples R China

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 27期

基金：

中国国家自然科学基金;

关键词：

biocompatibility; core-shell nanostructures; surface modification; dual-mode targeted imaging; NANOCRYSTALS; DELIVERY;

D O I：

10.1002/adma.201501779

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Core-shell upconversion nanoparticle@metal-organic framework (UCNP@MOF) nanostructures are constructed by coating hexagonal NaYF4:Yb,Er nanoparticle (NP) cores with amino-functionalized iron carboxylate MOF shells. These nanostructures combine the near-infrared optical property of the UCNP cores and the T2-magnetic response (MR) imaging property of the MOF shells. After surface modification, the core-shell nanostructures are demonstrated as high-resolution nanoprobes for targeted luminescence/MR imaging both in vitro and in vivo. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4075 / 4080

页数：6