Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging

被引：368
作者：
Li, Yantao [1 ]
Tang, Jinglong [1 ]
He, Liangcan [1 ]
Liu, Yong [1 ]
Liu, Yaling [1 ]
Chen, Chunying [1 ]
Tang, Zhiyong [1 ]
机构：
[1] Chinese Acad Sci, Natl Ctr Nanosci & Technol, Key Lab Nanosyst & Hierarch Fabricat, Beijing 100190, Peoples R China
来源：
ADVANCED MATERIALS | 2015年 / 27卷 / 27期
基金：
中国国家自然科学基金;
关键词：
biocompatibility; core-shell nanostructures; surface modification; dual-mode targeted imaging; NANOCRYSTALS; DELIVERY;
D O I：
10.1002/adma.201501779
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Core-shell upconversion nanoparticle@metal-organic framework (UCNP@MOF) nanostructures are constructed by coating hexagonal NaYF4:Yb,Er nanoparticle (NP) cores with amino-functionalized iron carboxylate MOF shells. These nanostructures combine the near-infrared optical property of the UCNP cores and the T2-magnetic response (MR) imaging property of the MOF shells. After surface modification, the core-shell nanostructures are demonstrated as high-resolution nanoprobes for targeted luminescence/MR imaging both in vitro and in vivo. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：4075 / 4080
页数：6
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