Velocity navigator for motion compensated thermometry

被引:10
作者
Maier, Florian [1 ]
Krafft, Axel J. [1 ]
Yung, Joshua P. [2 ,3 ]
Stafford, R. Jason [2 ]
Elliott, Andrew [2 ]
Dillmann, Ruediger [4 ]
Semmler, Wolfhard [1 ]
Bock, Michael [1 ]
机构
[1] German Canc Res Ctr, D-69120 Heidelberg, Germany
[2] Univ Texas MD Anderson Canc Ctr, Dept Imaging Phys, Houston, TX 77030 USA
[3] Univ Texas Houston, Grad Sch Biomed Sci, Houston, TX USA
[4] Karlsruhe Inst Technol, Inst Anthropomat, Karlsruhe, Germany
关键词
Interventional MRI; Thermometry; Motion compensation; Kalman filter; FOCUSED ULTRASOUND; THERMAL ABLATION; ONLINE CORRECTION; LIVER;
D O I
10.1007/s10334-011-0245-z
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Object Proton resonance frequency shift thermometry is sensitive to breathing motion that leads to incorrect phase differences. In this work, a novel velocity-sensitive navigator technique for triggering MR thermometry image acquisition is presented. Materials and methods A segmented echo planar imaging pulse sequence was modified for velocity-triggered temperature mapping. Trigger events were generated when the estimated velocity value was less than 0.2 cm/s during the slowdown phase in parallel to the velocity-encoding direction. To remove remaining high-frequency spikes from pulsation in real time, a Kalman filter was applied to the velocity navigator data. A phantom experiment with heating and an initial volunteer experiment without heating were performed to show the applicability of this technique. Additionally, a breath-hold experiment was conducted for comparison. Results A temperature rise of Delta T = +37.3 degrees C was seen in the phantom experiment, and a root mean square error (RMSE) outside the heated region of 2.3 degrees C could be obtained for periodic motion. In the volunteer experiment, a RMSE of 2.7 degrees C/2.9 degrees C (triggered vs. breath hold) was measured. Conclusion A novel velocity navigator with Kalman filter postprocessing in real time significantly improves the temperature accuracy over non-triggered acquisitions and suggests being comparable to a breath-held acquisition. The proposed technique might be clinically applied for monitoring of thermal ablations in abdominal organs.
引用
收藏
页码:15 / 22
页数:8
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