Adjuvant treatment and survival in older women with triple negative breast cancer: A Surveillance, Epidemiology, and End Results analysis

被引：12

作者：

Kozak, Margaret M. ^{[1
]}

Xiang, Michael ^{[1
]}

Pollom, Erqi L. ^{[1
]}

Horst, Kathleen C. ^{[1
]}

机构：

[1] Stanford Canc Inst, Dept Radiat Oncol, Stanford, CA 94305 USA

来源：

BREAST JOURNAL | 2019年 / 25卷 / 03期

关键词：

breast cancer; chemotherapy; outcomes; radiation treatment; triple negative; CHEMOTHERAPY; OUTCOMES; AGE;

D O I：

10.1111/tbj.13251

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Patients with triple negative breast cancer were identified using the Surveillance, Epidemiology, and End Results database. Competing risks analysis was used to assess the cumulative incidence of breast cancer-specific mortality (BCSM). Multivariable Fine-Gray regression was used to identify predictors of BCSM. Women age 70+ (n = 4221) were less likely to receive chemotherapy and radiation treatment (P < 0.0001) and had higher BCSM compared to younger women (P < 0.0001). There were no differences in BCSM in patients who received adjuvant treatment (P = 0.10). Stage II patients derived the greatest relative and absolute benefit from adjuvant treatment. Age was not a significant predictor of BCSM.

引用

页码：469 / 473

页数：5

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