Long-term stability of biomarkers of the iron status in human serum and plasma

被引：16
|
作者：
Jansen, Eugene H. J. M. [1 ]
Beekhof, Piet K. [1 ]
Schenk, Erna [1 ]
机构：
[1] Natl Inst Publ Hlth & Environm, Ctr Hlth Protect, NL-3720 BA Bilthoven, Netherlands
来源：
BIOMARKERS | 2013年 / 18卷 / 04期
关键词：
Ceruloplasmin; ferritin; haptoglobin; storage; total iron; transferrin; transferrin receptor; UIBC; CARDIOVASCULAR-DISEASE; RISK; ANALYTES; STORES; TRANSFERRIN; STORAGE; CANCER; COHORT; TUBES; WOMEN;
D O I：
10.3109/1354750X.2013.781223
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Context: In epidemiological research, it is very important to test the stability of biomarkers as function of both storage time and temperature. Objective: In this study, the stability of biomarkers of the iron status was tested up to 1 year of storage. Materials and methods: The biomarkers include total iron, unsaturated iron binding capacity, ferritin, transferrin, soluble transferrin receptor, ceruloplasmin and haptoglobin. Results: The concentrations of all biomarkers tested remain constant upon storage at -20, -70 and -196 degrees C. Conclusion: All biomarkers of the iron status were stable at the temperatures tested for 1 year.
引用
收藏
页码：365 / 368
页数：4
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