Design and implementation of the ELSA-Brasil biobank: a prospective study in a Brazilian population

被引：16

作者：

Pereira, Alexandre C. ^{[1
,2
]}

Bensenor, Isabela M. ^{[2
]}

Fedeli, Ligia M. ^{[2
]}

Castilhos, Cristina ^{[3
]}

Vidigal, Pedro G. ^{[4
]}

Maniero, Viviane ^{[5
]}

Leite, Claudia M. ^{[6
]}

Pimentel, Robercia A. ^{[7
]}

Duncan, Bruce B. ^{[3
]}

Mill, Jose Geraldo ^{[6
]}

Lotufo, Paulo A. ^{[2
]}

机构：

[1] Univ Sao Paulo, Univ Hosp, Ctr Pesquisa Clin & Epidemiol, Sao Paulo, Brazil

[2] Univ Sao Paulo, Inst Coracao, Mol Biol Lab, Sao Paulo, Brazil

[3] Univ Fed Rio Grande do Sul, Programa Posgrad Epidemiol, Fac Med, Porto Alegre, RS, Brazil

[4] Univ Fed Minas Gerais, Fac Med, Dept Clin Med, Belo Horizonte, MG, Brazil

[5] Fundacao Oswaldo Cruz, Rio De Janeiro, RJ, Brazil

[6] Univ Fed Espirito Santo, Ctr Biomed, Vitoria, ES, Brazil

[7] Univ Fed Bahia, Salvador, BA, Brazil

来源：

REVISTA DE SAUDE PUBLICA | 2013年 / 47卷

关键词：

Biological Specimen Banks; organization & administration Biological Markers; Hematologic Tests; Medical Examination; analysis; Multicenter Studies as Topic; methods; Cohort Studies;

D O I：

10.1590/S0034-8910.2013047003822

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The Brazilian Longitudinal Study for Adult Health (ELSA-Brasil) is a multicenter prospective cohort of civil servants designed to assess the determinants of chronic diseases, especially cardiovascular diseases and type 2 diabetes. The present article describes the main design and implementation points of the ELSA-Brasil biobank project. Economic, political, logistical and technological aspects of this study are characterized. Additionally, it discusses the final biorepository protocol and the facilities implemented to achieve this objective. The design and implementation process of the ELSA-Brasil biobank took three years to be performed. Both the central and local biobanks were built according to the best biorepository techniques, using different technological solutions for the distinct needs expected in this study.

引用

页码：72 / 78

页数：7

共 6 条

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