Apoptosome: The seven-spoked death machine

被引：49

作者：

Salvesen, GS ^{[1
]}

Renatus, M ^{[1
]}

机构：

[1] Burnham Inst, Program Apoptosis & Cell Death Res, La Jolla, CA 92037 USA

来源：

DEVELOPMENTAL CELL | 2002年 / 2卷 / 03期

关键词：

D O I：

10.1016/S1534-5807(02)00137-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A paper in the February issue of Molecular Cell describes the structure of the apoptosome, a multicomponent death machine, deciphered by cryoelectron microscopy. This structure explains the assembly of the machine, the tentative location of the subcomponents, and proposes a mechanism for initiating the death signal.

引用

页码：256 / 257

页数：2

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