Massive creatine kinase elevations with quetiapine:: Report of two cases -: A case report

被引：16

作者：

Klein, JP

Fiedler, U

Appel, H

Quante, A

Jockers-Scherübl, MC

机构：

[1] Charite Univ Med Berlin, Dept Psychiat & Psychotherapy, Berlin, Germany

[2] Charite Univ Med Berlin, Dept Gastroenterol & Rheumatol, Berlin, Germany

来源：

PHARMACOPSYCHIATRY | 2006年 / 39卷 / 01期

关键词：

D O I：

10.1055/s-2006-931478

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Massive elevations of serum creatine kinase (CK) can occur in a significant number of patients treated with neuroleptics in the absence of neuroleptic malignant syndrome (NMS). We report two cases of CK-elevations associated with quetiapine treatment, which disappeared after drug discontinuation. To our knowledge, case number one is the first case of quetiapine-induced CK elevation in a neuroleptic-naive patient. We thus suggest CK assessment when myalgia occurs with neuroleptic treatment.

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页码：39 / 40

页数：2

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