Oxidative Stress Response Induced by Butachlor in Zebrafish Embryo/Larvae: The Protective Effect of Vitamin C

被引：16
|
作者：
Xiang, Qingqing [1 ]
Xu, Bofan [1 ]
Ding, Yilun [3 ]
Liu, Xiaoyi [1 ]
Zhou, Ying [1 ,2 ]
Ahmad, Farooq [4 ]
机构：
[1] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310032, Zhejiang, Peoples R China
[2] Zhejiang Univ Technol, Res Ctr Anal & Measurement, Hangzhou 310032, Zhejiang, Peoples R China
[3] Montverde Acad Shanghai, Shanghai 201702, Peoples R China
[4] Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, State Key Lab Met Matrix Composites, 800 Dongchuan Rd, Shanghai, Peoples R China
来源：
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 2018年 / 100卷 / 02期
关键词：
Butachlor; Oxidative stress; Protective effect; Vitamin C; Zebrafish; HERBICIDE BUTACHLOR; ACUTE TOXICITY; HUMAN ERYTHROCYTES; DANIO-RERIO; IN-VITRO; WATER; CHLORPYRIFOS; EXPOSURE; ASSAY; GC;
D O I：
10.1007/s00128-017-2245-9
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
The widespread contamination and persistence of the herbicide butachlor in the environment resulted in the exposure of non-target organisms. The present study investigated the toxicity effect of butachlor (1-15 A mu mol/L) and the protective effect of vitamin C (VC) against butachlor-induced toxicity in zebrafish. It was found that butachlor significantly increased the mortality and malformation rates in a dose-dependent manner, which caused elevation in reactive oxygen species (ROS) and malondialdehyde (MDA) after 72 h exposure. Compared with butachlor treatment group, the protective effect of VC against butachlor-induced toxicity were observed after adding 40, 80 mg/L VC respectively. VC significantly decreased the mortality, malformation rates, ROS, MDA, and normalized antioxidant enzymes activities of zebrafish after 72 h exposure. The result shows VC has mitigative effect on butachlor-induced toxicity and it can be used as an effective antioxidant in aquaculture.
引用
收藏
页码：208 / 215
页数：8
相关论文
共 50 条
  • [1] Oxidative Stress Response Induced by Butachlor in Zebrafish Embryo/Larvae: The Protective Effect of Vitamin C
    Qingqing Xiang
    Bofan Xu
    Yilun Ding
    Xiaoyi Liu
    Ying Zhou
    Farooq Ahmad
    Bulletin of Environmental Contamination and Toxicology, 2018, 100 : 208 - 215
  • [2] Fipronil induced oxidative stress in kidney and brain of mice: Protective effect of vitamin E and vitamin C
    Badgujar, Prarabdh C.
    Pawar, Nitin N.
    Chandratre, Gauri A.
    Telang, A. G.
    Sharma, A. K.
    PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2015, 118 : 10 - 18
  • [3] Protective effect of marine algae phlorotannins against AAPH-induced oxidative stress in zebrafish embryo
    Kang, Min-Cheol
    Cha, Seon Heui
    Wijesinghe, W. A. J. P.
    Kang, Sung-Myung
    Lee, Seung-Hong
    Kim, Eun-A.
    Song, Choon Bok
    Jeon, You-Jin
    FOOD CHEMISTRY, 2013, 138 (2-3) : 950 - 955
  • [4] Oxidative stress response induced by atrazine in Palaemonetes argentinus: The protective effect of vitamin E
    Griboff, Julieta
    Morales, David
    Bertrand, Lidwina
    Ines Bonansea, Rocio
    Victoria Monferran, Magdalena
    Asis, Ramon
    Alberto Wunderlin, Daniel
    Valeria Ame, Maria
    ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2014, 108 : 1 - 8
  • [5] Nano-TiO2 aggravates bioaccumulation and developmental neurotoxicity of difenoconazole in zebrafish larvae via oxidative stress and apoptosis: Protective role of vitamin C
    Zhu, Renfei
    Liu, Chunlan
    Wang, Jingyu
    Zou, Li
    Yang, Fan
    Chi, Xia
    Zhu, Jiansheng
    ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 251
  • [6] Protective effect of vitamin C against chlorpyrifos oxidative stress in male mice
    Aly, Nagat
    EL-Gendy, Kawther
    Mahmoud, Fatma
    El-Sebae, Abdel Khalek
    PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2010, 97 (01) : 7 - 12
  • [7] Vitamin C Mitigates Oxidative Stress and Behavioral Impairments Induced by Deltamethrin and Lead Toxicity in Zebrafish
    Paduraru, Emanuela
    Flocea, Elena-Iuliana
    Lazado, Carlo C.
    Simionov, Ira-Adeline
    Nicoara, Mircea
    Ciobica, Alin
    Faggio, Caterina
    Jijie, Roxana
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (23)
  • [8] Ameliorating Effect of Vitamin C Against Potassium Dichromate Induced Oxidative Stress and Inflammatory Response in Rats
    Al Jameil, Noura
    Tabassum, Hajera
    Fatima, Sabiha
    Ali, Mir Naiman
    Rizwana, Humaira
    Khan, Farah Aziz
    INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2017, 13 (08) : 990 - 999
  • [9] Protective Effect of Vitamin C on Oxidative Stress: a Randomized Controlled Trial
    Sasazuki, Shizuka
    Hayashi, Tomonori
    Nakachi, Kei
    Sasaki, Satoshi
    Tsubono, Yoshitaka
    Okubo, Shunji
    Hayashi, Masato
    Tsugane, Shoichiro
    INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH, 2008, 78 (03) : 121 - 128
  • [10] The Protective Effect of Vitamin C on Azoxymethane-induced Oxidative Stress in Colon of Mice
    Karabulut, Aysun Bay
    Ozgor, Dincer
    Ara, Cengiz
    Dirican, Abuzer
    Kahraman, Latif
    Yaman, Hilmi
    ERCIYES MEDICAL JOURNAL, 2009, 31 (04) : 305 - 309
12345