Solution thermodynamics of valnemulin hydrogen fumarate in different pure solvents

被引：19
作者：
Ouyang, Jinbo [1 ,2 ]
Wang, Jingkang [1 ,2 ]
Huang, Xin [1 ]
Bao, Ying [1 ,2 ]
Wang, Yongli [1 ,2 ]
Yin, Qiuxiang [1 ,2 ]
Liu, Ailing [3 ]
Li, Xudong [3 ]
Hao, Hongxun [1 ,2 ]
机构：
[1] Tianjin Univ, Sch Chem Engn & Technol, State Key Lab Chem Engn, Tianjin 300072, Peoples R China
[2] Collaborat Innovat Ctr Chem Sci & Chem Engn, Tianjin 300072, Peoples R China
[3] Tianjin Ringpu Biotechnol CO LTD, Tianjin 300072, Peoples R China
来源：
JOURNAL OF CHEMICAL THERMODYNAMICS | 2015年 / 91卷
基金：
中国国家自然科学基金;
关键词：
Valnemulin hydrogen fumarate; Solubility; Enthalpy; Entropy; Gibbs energy; ORGANIC-SOLVENTS; LIQUID-MIXTURES; DIFFERENT TEMPERATURES; SOLUBILITY; EQUILIBRIUM; EXPRESSION; METHANOL; EQUATION; ETHANOL; SYSTEMS;
D O I：
10.1016/j.jct.2015.07.023
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
Solubility of valnemulin hydrogen fumarate in five pure solvents was determined within temperature range of (278.15 to 323.15) K by a gravimetric method. The results show that the solubility of valnemulin hydrogen fumarate in tested pure solvents increases with the increasing temperature. The solubility values were correlated by the Wilson model, NRTL model and UNIQUAC model. The UNIQUAC volume parameter, area parameter, and Wilson liquid molar volume parameter of valnemulin hydrogen fumarate were estimated by the group contribution method. It was found that the correlated results are in good agreement with the experimental results. Furthermore, the mixing thermodynamic properties of valnemulin hydrogen fumarate in solutions, including the mixing Gibbs energy, the mixing enthalpy and entropy, were determined by using the Wilson model and the experimental solubility results. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：73 / 79
页数：7
相关论文
共 50 条
  • [21] Correlation of solubility data and solution properties of chlorzoxazone in pure solvents
    Dhayananth, N.
    Karthika, S.
    Kalaichelvi, P.
    Radhakrishnan, T. K.
    JOURNAL OF CHEMICAL THERMODYNAMICS, 2022, 170
  • [22] Characterization and In vivo Evaluation of Polymorphic Valnemulin Hydrogen Fumarate
    Zhu, Xinle
    Zhang, Li
    Li, Jian
    Zhao, Hui
    Gu, Jinhua
    Wang, Hejia
    CURRENT DRUG DELIVERY, 2024,
  • [23] Solubility of a poorly soluble immunosuppressant in different pure solvents: Measurement, correlation, thermodynamics and molecular interactions
    Abul Kalam, Mohd
    Khan, Abdul Arif
    Alshamsan, Aws
    Haque, Anzarul
    Shakeel, Faiyaz
    JOURNAL OF MOLECULAR LIQUIDS, 2018, 249 : 53 - 60
  • [24] Solubility determination, model evaluation and solution thermodynamics of isovanillin in 15 pure solvents and 4 binary solvents
    Zhang, Shihao
    Wang, Huiqi
    Dai, Jiayu
    Niu, Yue
    Yin, Qiuxiang
    Zhou, Ling
    JOURNAL OF MOLECULAR LIQUIDS, 2021, 340
  • [25] Thermodynamics of pharmaceuticals: Prediction of solubility in pure and mixed solvents with PC-SAFT
    Spyriouni, Theodora
    Krokidis, Xenophon
    Economou, Ioannis G.
    FLUID PHASE EQUILIBRIA, 2011, 302 (1-2) : 331 - 337
  • [26] Solubility and thermodynamic properties of maltol in different pure solvents
    Li, Jing
    Hao, Hongxun
    Guo, Nannan
    Wang, Na
    Hao, Yunhui
    Luan, Yanan
    Chen, Kui
    Huang, Xin
    JOURNAL OF MOLECULAR LIQUIDS, 2017, 243 : 313 - 323
  • [27] Transfer Thermodynamics of Triclosan from Water to Organic Solvents with Different Hydrogen Bonding Capability
    Delgado, Daniel R.
    Sosnik, Alejandro
    Martinez, Fleming
    LATIN AMERICAN JOURNAL OF PHARMACY, 2011, 30 (03): : 459 - 466
  • [28] Solution thermodynamics of tris-(2,4-ditert-butylphenyl)-phosphite in a series of pure solvents
    Yang, Jinyue
    Hou, Baohong
    Huang, Jingjing
    Li, Xin
    Tian, Beiqian
    Wang, Na
    Bi, Jingtao
    Hao, Hongxun
    JOURNAL OF MOLECULAR LIQUIDS, 2019, 283 : 713 - 724
  • [29] Measurement, correlation and dissolution thermodynamics of biological active chalcone in organic solvents at different temperatures
    Bhesaniya, K. D.
    Nandha, K.
    Baluja, S.
    JOURNAL OF CHEMICAL THERMODYNAMICS, 2014, 74 : 32 - 38
  • [30] Solubility, solubility parameters and solution thermodynamics of thymoquinone in different mono solvents
    Ahmad, Ajaz
    Raish, Mohammad
    Alkharfy, Khalid M.
    Alsarra, Ibrahim A.
    Khan, Altaf
    Ahad, Abdul
    Jan, Basit L.
    Shakeel, Faiyaz
    JOURNAL OF MOLECULAR LIQUIDS, 2018, 272 : 912 - 918
12345