Mutagenesis Of The Cleavage Site Of (pro)renin Receptor Abrogates Aldosterone-salt-induced Hypertension And Renal Injury In Mice

被引:0
|
作者
Fu, Ziwei
Zheng, Huaqing
Yang, Tianxin
机构
关键词
Hypertension; resistantHypertension:experimental; Sodium channel; Aldosterone;
D O I
10.1161/hyp.79.suppl_1.031
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
A031
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Mineralocorticoid receptor activation: a major contributor to salt-induced renal injury and hypertension in young rats
    Kawarazaki, Hiroo
    Ando, Katsuyuki
    Fujita, Megumi
    Matsui, Hiromitsu
    Nagae, Ai
    Muraoka, Kazuhiko
    Kawarasaki, Chiaki
    Fujita, Toshiro
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2011, 300 (06) : F1402 - F1409
  • [32] Site-1 Protease-derived Soluble (pro) Renin Receptor Mediates Aldosterone-induced Enac Activation In The Collecting Duct
    Wang Fei
    Luo Renfei
    Peng Kexin
    Wu Peng
    Liu Xiyang
    Soodvilai, Sunhapas
    Wang, Wen-Hui H.
    Yang Tianxin
    HYPERTENSION, 2020, 76
  • [33] Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin-angiotensin system
    Wang, Fei
    Lu, Xiaohan
    Liu, Mi
    Feng, Yumei
    Zhou, Shu-Feng
    Yang, Tianxin
    BMC MEDICINE, 2015, 13
  • [34] Crosstalk between (Pro)renin receptor and COX-2 in the renal medulla during angiotensin II-induced hypertension
    Yang, Tianxin
    CURRENT OPINION IN PHARMACOLOGY, 2015, 21 : 89 - 94
  • [35] Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats
    Kawarazaki, Hiroo
    Ando, Katsuyuki
    Nagae, Ai
    Fujita, Megumi
    Matsui, Hiromitsu
    Fujita, Toshiro
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2010, 25 (09) : 2879 - 2889
  • [36] Neuron Specific (Pro)renin Receptor Knockout Reduces Sodium Appetite and Attenuates the Development of DOCA-salt Induced Hypertension.
    Trebak, Fatima
    Li, Wencheng
    Feng, Yumei
    HYPERTENSION, 2017, 70
  • [37] Increased renal injury with AT1 receptor blockade in salt-sensitive hypertension but not L-NAME-induced hypertension
    Rudd, MA
    Maitland, K
    Davis, W
    Loscalzo, J
    HYPERTENSION, 2005, 46 (04) : 826 - 826
  • [38] Site-1 Protease-Derived Soluble (Pro)Renin Receptor Contributes to Salt-Sensitive Hypertension via Activation of the Intrarenal RAS
    Wang, Fei
    Peng, Kexin
    Xie, Shiying
    Yang, Kevin
    Luo, Renfei
    Yang, Tianxin
    HYPERTENSION, 2018, 72
  • [40] Augmented Tubular Renin-Angiotensin System in Salt-Induced Renal Injury and Prevention by Angiotensin II Receptor Blockade
    Susic, Dinko
    Frohlich, Edward
    Kobori, Hiroyuki
    Shao, Weijian
    Seth, Dale
    Navar, L. Gabriel
    HYPERTENSION, 2009, 54 (04) : E48 - E49