Models of grid cells and theta oscillations

被引：33

作者：

Barry, Caswell ^{[1
,2
,3
]}

Bush, Daniel ^{[1
,2
]}

O'Keefe, John ^{[4
,5
]}

Burgess, Neil ^{[1
,2
]}

机构：

[1] UCL Inst Cognit Neurosci, London WC1N 3AR, England

[2] UCL, Inst Neurol, London WC1N 3BG, England

[3] UCL, Inst Behav Neurosci, London WC1H 0AP, England

[4] UCL, Dept Cell & Dev Biol, London WC1E 6BT, England

[5] UCL, Sainsbury Wellcome Ctr Neural Circuits & Behav, London WC1E 6BT, England

来源：

NATURE | 2012年 / 488卷 / 7409期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

ENTORHINAL CORTEX; INTERFERENCE;

D O I：

10.1038/nature11276

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Arising from M. M.Yartsev, M. P. Witter &N. Ulanovsky 479, 103-107 (2011)Grid cells recorded in the medial entorhinal cortex (MEC) of freely moving rodents show a markedly regular spatial firing pattern whose underlying mechanism has been the subject of intense interest. Yartsev et al. report that the firing of grid cells in crawling bats does not show theta rhythmicity “causally disproving a major class of computational models” of grid cell firing that rely on oscillatory interference. However, their data may be consistent with these models, with the apparent lack of theta rhythmicity reflecting slow movement speeds and low firing rates. Thus, the conclusion of Yartsev et al. is not supported by their data. © 2012 Macmillan Publishers Limited. All rights reserved.

引用

页码：E1 / E2

页数：2

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