Expression of amplified esterase genes in insecticide resistant Myzus persicae (Sulzer)

被引:0
作者
Field, LM [1 ]
Hick, CA [1 ]
Devonshire, AL [1 ]
Javed, N [1 ]
Spence, JM [1 ]
Blackman, RL [1 ]
机构
[1] NAT HIST MUSEUM,DEPT ENTOMOL,LONDON SW7 5BD,ENGLAND
来源
MOLECULAR GENETICS AND EVOLUTION OF PESTICIDE RESISTANCE | 1996年 / 645卷
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中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
Insecticide resistance in Myzus persicae results from amplification of genes encoding insecticide-detoxifying esterases and from differential transcription of the amplified genes which may be mediated by changes in DNA methylation. Methylation is usually stable in resistant aphid clones and can be inherited during sexual reproduction. However, when a sudden loss of methylation occurs within a clone, it is accompanied by silencing of the amplified genes. When reselected with insecticides some recovery of expression can occur but this is not accompanied by methylation. Some aphid clones have amplified esterase genes arranged as tandem repeats at a single locus, whereas others have arrays dispersed around the genome. Thus, although resistance in M. persicae is dependent primarily on gene amplification, this may be modulated by other molecular and genetic factors.
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页码:72 / 78
页数:7
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