The Olig family affects central nervous system development and disease

被引:12
|
作者
Tan, Botao [1 ]
Yu, Jing [1 ]
Yin, Ying [1 ]
Jia, Gongwei [1 ]
Jiang, Wei [1 ]
Yu, Lehua [1 ]
机构
[1] Chongqing Med Univ, Dept Rehabil Med, Affiliated Hosp 2, Chongqing 400010, Peoples R China
基金
中国国家自然科学基金;
关键词
nerve regeneration; brain injury; spinal cord injury; review; Olig family; oligodendrocytes; astrocytes; central nervous system disease; demyelination; development; differentiation; NSFC grant; neural regeneration; NEURAL STEM-CELLS; SPINAL-CORD-INJURY; BHLH TRANSCRIPTION FACTOR; OLIGODENDROCYTE PRECURSOR CELLS; MOTOR-NEURON; PROGENITOR CELLS; ASTROCYTE DEVELOPMENT; SUBVENTRICULAR ZONE; MALIGNANT GLIOMA; ADULT ZEBRAFISH;
D O I
10.4103/1673-5374.128232
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Neural cell differentiation and maturation is a critical step during central nervous system development. The oligodendrocyte transcription family (Olig family) is known to be an important factor in regulating neural cell differentiation. Because of this, the Olig family also affects acute and chronic central nervous system diseases, including brain injury, multiple sclerosis, and even gliomas. Improved understanding about the functions of the Olig family in central nervous system development and disease will greatly aid novel breakthroughs in central nervous system diseases. This review investigates the role of the Olig family in central nervous system development and related diseases.
引用
收藏
页码:329 / 336
页数:8
相关论文
共 50 条
  • [1] The Olig family affects central nervous system development and disease
    Botao Tan
    Jing Yu
    Ying Yin
    Gongwei Jia
    Wei Jiang
    Lehua Yu
    NeuralRegenerationResearch, 2014, 9 (03) : 329 - 336
  • [2] Notch Signaling in Central Nervous System: From Cellular Development to Multiple Sclerosis Disease
    Askari, Hamid
    Rabiei, Fatemeh
    Yahyazadeh, Masoomeh
    Biagini, Giuseppe
    Ghasemi-Kasman, Maryam
    CURRENT NEUROPHARMACOLOGY, 2025, 23 (01) : 3 - 19
  • [3] The Effects of the Olig Family on the Regulation of Spinal Cord Development and Regeneration
    Liu, Yuan
    Long, Zai-Yun
    Yang, Ce
    NEUROCHEMICAL RESEARCH, 2021, 46 (11) : 2776 - 2782
  • [4] Regulation of Glial Function by Noncoding RNA in Central Nervous System Disease
    Bai, Ying
    Ren, Hui
    Bian, Liang
    Zhou, You
    Wang, Xinping
    Xiong, Zhongli
    Liu, Ziqi
    Han, Bing
    Yao, Honghong
    NEUROSCIENCE BULLETIN, 2023, 39 (03) : 440 - 452
  • [5] The role of annexins in central nervous system development and disease
    White II, Zachary B.
    Nair, Sindhu
    Bredel, Markus
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2024, 102 (06): : 751 - 760
  • [6] Neuroinflammation and central nervous system regeneration in vertebrates
    Kyritsis, Nikos
    Kizil, Caghan
    Brand, Michael
    TRENDS IN CELL BIOLOGY, 2014, 24 (02) : 128 - 135
  • [7] Complement dysregulation in the central nervous system during development and disease
    Lee, John D.
    Coulthard, Liam G.
    Woodruff, Trent M.
    SEMINARS IN IMMUNOLOGY, 2019, 45
  • [8] Microglia: Housekeeper of the Central Nervous System
    Kabba, John Alimamy
    Xu, Yazhou
    Christian, Handson
    Ruan, Wenchen
    Chenai, Kitchen
    Xiang, Yun
    Zhang, Luyong
    Saavedra, Juan M.
    Pang, Tao
    CELLULAR AND MOLECULAR NEUROBIOLOGY, 2018, 38 (01) : 53 - 71
  • [9] Central Nervous System Remyelination: Roles of Glia and Innate Immune Cells
    Baaklini, Charbel S.
    Rawji, Khalil S.
    Duncan, Greg J.
    Ho, Madelene F. S.
    Plemel, Jason R.
    FRONTIERS IN MOLECULAR NEUROSCIENCE, 2019, 12
  • [10] Cell death in glioblastoma and the central nervous system
    Malone, Kyle
    LaCasse, Eric
    Beug, Shawn T.
    CELLULAR ONCOLOGY, 2025, 48 (02) : 313 - 349