Ready Synthetic Access to Enantiopure Allylic α(F)-Branched Fluoroalkenes

被引：19

作者：

Larnaud, Florent ^{[1
,2
,3
]}

Malassis, Julien ^{[1
,2
,3
]}

Pfund, Emmanuel ^{[1
,2
]}

Linclau, Bruno ^{[3
]}

Lequeux, Thierry ^{[1
,2
]}

机构：

[1] Univ Caen Basse Normandie, UMR CNRS 6507, Lab Chim Mol & Thioorgan, F-14050 Caen, France

[2] Univ Caen Basse Normandie, FR3038, ENSICAEN, F-14050 Caen, France

[3] Univ Southampton, Southampton SO17 1BJ, Hants, England

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 10期

关键词：

NUCLEOPHILIC FLUOROALKYLATION; CHEMISTRY; FLUORINE;

D O I：

10.1021/ol400917j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Convenient access to homochiral fluoroalkenes is described via a Julia-Kocienski olefination reaction. The required homochiral fluorosulfone is synthesized by a Mitsunobu reaction from readily available enantiopure secondary alcohols.

引用

页码：2450 / 2453

页数：4

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