Regression of atherosclerotic plaques after lentivirus-mediated RNA interference of Cyclophilin A in ApoE-/- mice

被引:5
作者
Yan, Jinchuan [1 ]
Li, Ying [1 ]
Wang, Cuiping [1 ]
Wang, Zhongqun [1 ]
Yuan, Wei [1 ]
机构
[1] Jiangsu Univ, Affiliated Hosp, Dept Cardiol, Zhenjiang, Peoples R China
基金
中国国家自然科学基金;
关键词
Cyclophilin A; Atherosclerosis; Small interfering RNA; Inflammation;
D O I
10.1016/j.ijcard.2013.10.039
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:E87 / E90
页数:4
相关论文
共 9 条
[1]   Interfering with disease: a progress report on siRNA-based therapeutics [J].
de Fougerolles, Antonin ;
Vornlocher, Hans-Peter ;
Maraganore, John ;
Lieberman, Judy .
NATURE REVIEWS DRUG DISCOVERY, 2007, 6 (06) :443-453
[2]   Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector [J].
Kim, IH ;
Jozkowicz, A ;
Piedra, PA ;
Oka, K ;
Chan, L .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (23) :13282-13287
[3]   Use of lentiviral vectors for delivery of small interfering RNA [J].
Matta, H ;
Hozayev, B ;
Tomar, R ;
Chugh, P ;
Chaudhary, PM .
CANCER BIOLOGY & THERAPY, 2003, 2 (02) :206-210
[4]  
Oryoji K, 2013, MOD RHEUMATOL, DOI DOI 10.1007/S10165-013-0832-0
[5]   Enhanced Stabilization of Atherosclerotic Plaques in Apolipoprotein E-Knockout Mice by Combinatorial Toll-like Receptor-1 and-2 Gene Silencing [J].
Qi, Li Hang ;
Wang, Ying ;
Gao, Fei ;
Zhang, Cheng ;
Ding, Shi Fang ;
Ni, Mei ;
Feng, Jin Bo ;
Zhang, Yun .
HUMAN GENE THERAPY, 2009, 20 (07) :739-750
[6]  
Tong AW, 2005, CURR OPIN MOL THER, V7, P114
[7]   The clinical implications of increased cyclophilin A levels in patients with acute coronary syndromes [J].
Yan, Jinchuan ;
Zang, Xuan ;
Chen, Rui ;
Yuan, Wei ;
Gong, Jie ;
Wang, Cuiping ;
Li, Ying .
CLINICA CHIMICA ACTA, 2012, 413 (7-8) :691-695
[8]  
Yang JM, 2009, J CELL MOL MED S, V53, pA423
[9]   Antiapoptotic and Proapoptotic Signaling of Cyclophilin A in Endothelial Cells [J].
Yuan Wei ;
Yan Jinchuan ;
Liang Yi ;
Wu Jun ;
Wang Zhongqun ;
Wang Cuiping .
INFLAMMATION, 2013, 36 (03) :567-572