CSA Is Not Beneficial Long Term in Heart Failure Patients with Reduced Ejection Fraction

被引：6
作者：
Oldenburg, Olaf [1 ]
Coats, Andrew [2 ,3 ]
机构：
[1] Ruhr Univ Bochum, Clin Cardiol, Herz & Diabet Zentrum NRW, Georgstr 11, D-32545 Bad Oeynhausen, Germany
[2] Monash Univ, Clayton, Vic 3800, Australia
[3] Univ Warwick, Coventry CV4 7AL, W Midlands, England
来源：
INTERNATIONAL JOURNAL OF CARDIOLOGY | 2017年 / 227卷
关键词：
central sleep apnea; compensatory mechanism; heart failure; sleep; CENTRAL SLEEP-APNEA; CHEYNE-STOKES RESPIRATION; POSITIVE AIRWAY PRESSURE; SYMPATHETIC-NERVE ACTIVITY; VENTILATION; PREDICTORS; MANAGEMENT; MORTALITY; IMPACT; FRIEND;
D O I：
10.1016/j.ijcard.2016.11.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Central sleep apnea (CSA) affects many patients, with heart failure and results in hypoxia and nor-epinephrine release and is associated with high morbidity and mortality. Recent trials in the treatment of CSA using positive airway pressure therapies have failed to demonstrate improvement in mortality and as a result, the compensatory nature of CSA has been questioned. The detrimental effects from CSA are clear. While there may be a short term compensatory effect, the long term effects cause chronic insult to the cardiovascular system indicating that CSA should be treated, but alternative treatment options need to be considered. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：474 / 477
页数：4
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