Alzheimer?s disease;
phase three testing
of new drugs;
β
-amyloid;
tau protein;
neuroinflammatory theory;
ric symptoms;
neuroprotection;
BETA;
TRAMIPROSATE;
INHIBITION;
GUANFACINE;
DEMENTIA;
TRIAL;
D O I:
10.48095/cccsnn2022462
中图分类号:
Q189 [神经科学];
学科分类号:
071006 ;
摘要:
A new era of innovative treatment options for Alzheimer's disease is emerging. New goals of treatment are being developed with various monoclonal antibodies targeting potentially pathological molecules involved in the pathogenesis of Alzheimer's disease. The aim of this review is to acquaint the reader with new potential drugs, while most of those mentioned in this review are in the third phase of clinical trials.
机构:
Monash Univ, Fac Pharm & Pharmaceut Sci, Ctr Med Use & Safety, Parkville, Vic, Australia
Karolinska Inst, Aging Res Ctr, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden
Stockholm Univ, Stockholm, SwedenMonash Univ, Fac Pharm & Pharmaceut Sci, Ctr Med Use & Safety, Parkville, Vic, Australia
Tan, Edwin C. K.
Hilmer, Sarah N.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sydney, Dept Clin Pharmacol, St Leonards, NSW, Australia
Univ Sydney, Aged Care, Kolling Inst, Royal North Shore Hosp, St Leonards, NSW, Australia
Univ Sydney, Geriatr Pharmacol, St Leonards, NSW, Australia
Hornsby Ku Ring Gai Hosp, NHMRC Cognit Decline Partnership Ctr, Hornsby, NSW, AustraliaMonash Univ, Fac Pharm & Pharmaceut Sci, Ctr Med Use & Safety, Parkville, Vic, Australia
Hilmer, Sarah N.
Garcia-Ptacek, Sara
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机构:
Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Clin Geriatr, Stockholm, Sweden
Soder Sjukhuset, Neurol Sect, Dept Internal Med, Stockholm, SwedenMonash Univ, Fac Pharm & Pharmaceut Sci, Ctr Med Use & Safety, Parkville, Vic, Australia
Garcia-Ptacek, Sara
Bell, J. Simon
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机构:
Monash Univ, Fac Pharm & Pharmaceut Sci, Ctr Med Use & Safety, Parkville, Vic, Australia
Hornsby Ku Ring Gai Hosp, NHMRC Cognit Decline Partnership Ctr, Hornsby, NSW, Australia
Univ South Australia, Sch Pharm & Med Sci, Adelaide, SA, AustraliaMonash Univ, Fac Pharm & Pharmaceut Sci, Ctr Med Use & Safety, Parkville, Vic, Australia
机构:
Weill Cornell Med Coll, Med, New York, NY USAWeill Cornell Med Coll, Med, New York, NY USA
Romero, L.
Ergel, B.
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机构:
Weill Cornell Med Coll, Helen & Robert Appel Alzheimers Dis Res Inst, New York, NY USAWeill Cornell Med Coll, Med, New York, NY USA
Ergel, B.
Petsko, G.
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h-index: 0
机构:
Weill Cornell Med Coll, Helen & Robert Appel Alzheimers Dis Res Inst, New York, NY USA
Weill Cornell Med Coll, Dept Neurol, New York, NY USAWeill Cornell Med Coll, Med, New York, NY USA
机构:Prince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, Australia
Brodaty, H
Ames, D
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机构:Prince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, Australia
Ames, D
Boundy, KL
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机构:Prince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, Australia
Boundy, KL
Hecker, J
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机构:Prince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, Australia
Hecker, J
Snowdon, J
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机构:Prince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, Australia
Snowdon, J
Storey, E
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机构:Prince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, Australia
Storey, E
Yates, MW
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h-index: 0
机构:
Prince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, AustraliaPrince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, Australia