Perspectives on Treatment of Metastatic Castration-Resistant Prostate Cancer

被引:29
作者
Merseburger, Axel S. [1 ]
Bellmunt, Joaquim [2 ]
Jenkins, Cheryl [3 ]
Parker, Chris [4 ]
Fitzpatrick, John M. [5 ,6 ]
机构
[1] Hannover Med Sch, Dept Urol & Urol Oncol, D-30625 Hannover, Germany
[2] Univ Hosp Mar, Inst Invest Med, Med Oncol Serv, Barcelona, Spain
[3] Rocket Sci Med Commun, Wantage, Oxon, England
[4] Royal Marsden Natl Hlth Serv Fdn Trust, Sutton, Surrey, England
[5] Mater Misericordiae Hosp Univ Coll, Dept Surg, Dublin, Ireland
[6] Irish Canc Soc, Dublin, Ireland
关键词
Metastatic castration-resistant; Prostate cancer; Treatment; Docetaxel; Cabazitaxel; Abiraterone acetate; Enzalutamide; CIRCULATING TUMOR-CELLS; ANDROGEN RECEPTOR GENE; MITOXANTRONE PLUS PREDNISONE; PHASE-II TRIAL; CLINICAL-TRIALS; BONE METASTASES; SIPULEUCEL-T; SKELETAL COMPLICATIONS; ABIRATERONE ACETATE; INCREASED SURVIVAL;
D O I
10.1634/theoncologist.2012-0478
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The arrival of several new agents-cabazitaxel, abiraterone acetate, enzalutamide, and radium-223-is changing the treatment options and management of patients with metastatic castration-resistant prostate cancer (mCRPC). Many other novel agents are also being investigated. As new drugs become approved, new treatment strategies and markers to best select which patients will best respond to which drug are needed. This review article is a summary of a European Treatment Practices Meeting, which was convened to discuss these latest data on novel agents and current treatment strategies in the mCRPC setting.
引用
收藏
页码:558 / 567
页数:10
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