Polyurethane (PU) adhesives are commonly used in the manufacture of food packaging multilayer materials (laminates). The compounds present in 9 PU adhesives have been identified and a migration test has been carried out to evaluate the migration of the compounds to a food simulant (Tenax). Migration of compounds such as phthalates, triacetin and a residual isocyanate was observed in 3 of the 11 laminates studied. Studies carried out to check the effect of different packaging conditions on migration showed that neither vacuum nor pasteurization had any effect on migration to Tenax.