Insulin resistance induced by elevated free fatty acids is associated with changes in IRS-1 phosphorylation & PKC θ activation in vivo

被引:0
|
作者
Griffin, ME
Marcucci, MJ
Cline, GW
Bell, K
Barucci, N
Lee, D
Kraegen, EW
Gerald, SI
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1207
引用
收藏
页码:A276 / A276
页数:1
相关论文
共 50 条
  • [31] Failure of β-cell compensation for insulin resistance induced by elevated free fatty acids in obese subjects
    Cavaghan, MK
    Breda, E
    Ehrmann, DA
    Polonsky, KS
    DIABETES, 1999, 48 : A239 - A239
  • [32] Changes in tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 (IRS-1) and association of p85 subunit of phosphatidylinositol 3-kinase with IRS-1 after feeding in rat liver in vivo
    Ito, Y
    Ariga, M
    Takahashi, SI
    Takenaka, A
    Hidaka, T
    Noguchi, T
    JOURNAL OF ENDOCRINOLOGY, 1997, 154 (02) : 267 - 273
  • [33] ARE ELEVATED FREE FATTY-ACIDS IMPLICATED IN INSULIN RESISTANCE STATES
    ZAMBON, A
    HASHIMOTO, SI
    BRUNZELL, JD
    CLINICAL RESEARCH, 1993, 41 (01): : A27 - A27
  • [34] Peripheral insulin resistance in obese girls with hyperandrogenism is related to oxidative phosphorylation and elevated serum free fatty acids
    Cree-Green, Melanie
    Newcomer, Bradley R.
    Coe, Gregory
    Newnes, Lindsey
    Baumgartner, Amy
    Brown, Mark S.
    Pyle, Laura
    Reusch, Jane E.
    Nadeau, Kristen J.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2015, 308 (09): : E726 - E733
  • [35] alpha(2)-HSG inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor and IRS-1 in vivo.
    Mathews, ST
    Srinivas, PR
    Goustin, AS
    Grunberger, G
    DIABETES, 1996, 45 : 423 - 423
  • [36] Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK
    Hitomi, Hirofumi
    Mehta, Puja K.
    Taniyama, Yoshihiro
    Lassegue, Bernard
    Seidel-Rogol, Bonnie
    San Martin, Alejandra
    Griendling, Kathy K.
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2011, 301 (06): : C1415 - C1422
  • [37] Gene expression explains IRS-2, but not IRS-1, depletion in glucose- and insulin-induced insulin resistance
    Renström, F
    Burén, J
    Eriksson, JW
    DIABETES, 2004, 53 : A315 - A315
  • [38] MiR-183-5p Induced by Saturated Fatty Acids Hinders Insulin Signaling by Downregulating IRS-1 in Hepatocytes
    Mai Thi Nguyen
    Min, Kyung-Ho
    Lee, Wan
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (06)
  • [39] Regulation of IRS-1/SHP2 interaction and AKT phosphorylation in animal models of insulin resistance
    Lima, MHM
    Ueno, M
    Thirone, ACP
    Rocha, EM
    Carvalho, CRO
    Saad, MJA
    ENDOCRINE, 2002, 18 (01) : 1 - 12
  • [40] Regulation of IRS-1/SHP2 interaction and AKT phosphorylation in animal models of insulin resistance
    Maria Helena M. Lima
    Mirian Ueno
    Ana Cláudia P. Thirone
    Eduardo M. Rocha
    Carla Roberta O. Carvalho
    Mário J. A. Saad
    Endocrine, 2002, 18 : 1 - 12