Overweight, hirsutism and deep voice in a 13-year-old girl

被引：0
作者：
Baus, I. [1 ]
Claviez, A.
Welzel, M. [1 ]
Kulle, A. [1 ]
Moritz, J.
Leuschner, I. [2 ]
Engler, S. [3 ]
Riepe, F. G. [1 ]
Holterhus, P. -M. [1 ]
机构：
[1] Univ Klinikum Schleswig Holstein, Klin Allgemeine Padiatrie, Hormonzentrum Kinder & Jugendliche, D-24105 Kiel, Germany
[2] Univ Klinikum Schleswig Holstein, Kindertumorregister GPOH, Inst Pathol, D-24105 Kiel, Germany
[3] Univ Klinikum Schleswig Holstein, Klin Allgemeine Chirurg & Thoraxchirurg, Abt Kinderchirurg, D-24105 Kiel, Germany
来源：
MONATSSCHRIFT KINDERHEILKUNDE | 2012年 / 160卷 / 03期
关键词：
Androgen and cortisol-producing adrenal tumor; Cortisol; Hyperandrogenism; Virilization; Cushing's syndrome; ADRENAL-CORTICAL NEOPLASMS; CHILDHOOD; CHILDREN; GROWTH;
D O I：
10.1007/s00112-011-2570-8
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The case of an adolescent female with a hormone-producing adrenal tumor is reported. The patient was characterized by virilization and Cushing's syndrome. Dehydroepiandrosterone sulfate (DHEA-S) and androstenedione levels were considerably elevated but cortisol excretion showed only a moderate increase. The most common presenting sign of hormone-producing adrenal tumors is virilization particularly in combination with weight gain und accelerated growth velocity. A complete radical operation is the therapy of choice. The tumor was completely resected and 3.5 years after diagnosis there has been no recurrence.
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收藏
页码：211 / 214
页数：4
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