PEG/lecithin-liquid-crystalline composite hydrogels for quasi-zero-order combined release of hydrophilic and lipophilic drugs

被引：20

作者：

Zhang, Hongbin ^{[1
]}

Hao, Rui ^{[1
]}

Ren, Xiangkui ^{[2
]}

Yu, Li ^{[1
]}

Yang, Huai ^{[1
]}

Yu, Haifeng ^{[1
]}

机构：

[1] Peking Univ, Coll Engn, Dept Adv Mat & Nanotechnol, Beijing 100871, Peoples R China

[2] Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

RSC ADVANCES | 2013年 / 3卷 / 45期

关键词：

DELIVERY; THERAPY; SYSTEMS; STATES; WATER;

D O I：

10.1039/c3ra44080j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Liquid crystalline microphase formed in PEG/lecithin hydrogels provides suppressed release of hydrophilic drugs but accelerated release for lipophilic drugs, achieving quasi-zero-order release of drugs with different water solubility.

引用

页码：22927 / 22930

页数：4