Low-cost commercial glass beads as dosimeters in radiotherapy

被引:56
作者
Jafari, S. M. [1 ,2 ]
Bradley, D. A. [1 ,5 ]
Gouldstone, C. A. [3 ]
Sharpe, P. H. G. [3 ]
Alalawi, A. [1 ]
Jordan, T. J. [4 ]
Clark, C. H. [1 ,3 ,4 ]
Nisbet, A. [1 ,4 ]
Spyrou, N. M. [1 ]
机构
[1] Univ Surrey, Dept Phys, CNRP, Guildford GU2 7XH, Surrey, England
[2] Kabul Med Univ, Fac Med, Dept Radiol, Kabul, Afghanistan
[3] Natl Phys Lab, Teddington TW11 0LW, Middx, England
[4] Royal Surrey Cty Hosp NHS Trust, Dept Med Phys, Guildford GU2 7XX, Surrey, England
[5] Univ Malaya, Dept Phys, Kuala Lumpur 50603, Malaysia
关键词
Radiotherapy; Dosimetry; Glass beads; TLD; EPR; ELECTRON-SPIN-RESONANCE; CLEAR FUSED QUARTZ; ROD DETECTOR; PHOTON BEAMS; SILICA GLASS; THERMOLUMINESCENCE; LUMINESCENCE; THERAPY; TLD;
D O I
10.1016/j.radphyschem.2013.11.007
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Recent developments in advanced radiotherapy techniques using small field photon beams, require small detectors to determine the delivered dose in steep dose gradient fields. Commercially available glass jewellery beads exhibit thermoluminescent properties and have the potential to be used as dosimeters in radiotherapy due to their small size (< 5 mm), low cost, reusability and inert nature. This study investigated the dosimetric characteristics of glass beads. The beads were irradiated by 6 MV photons using a medical linear-accelerator and Co-60 gamma rays over doses ranging from 1 to 2500 cGy. A thermoluminescence (TL) system and an electron paramagnetic resonance (EPR) system were employed for read out. Both the TL and EPR studies demonstrated a radiation-induced signal, the sensitivity of which varied with bead colour. White coloured beads proved to be the most sensitive for both systems. The smallest and therefore least sensitive bead sizes allowed measurement of doses of 1 cGy using the TL system while that for the EPR system was approximately 1000 cGy. The fading rate was found to be 10% 30 days after irradiation with both readout systems. The dose response is linear with measured dose over the dose range 1 to 2500 cGy, with an R2 correlation coefficient of greater than 0.999. The batch-to-batch reproducibility of a set of dosimeters after a single irradiation was found to be 3% (1 SD). The reproducibility of individual dosimeters was found to be 1.7%. No measurable angular dependence was found (results agreed within 1%). Dose rate response was found to agree within 1% for dose rates of 100 to 600 cGy/min. These results demonstrate the potential use of glass beads as TL dosimeters over the dose range commonly applied in radiotherapy. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:95 / 101
页数:7
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