Free radicals - Friends or foes? - Properties, functions, and secretion of human myeloperoxidase

被引：108
作者：
Arnhold, J
机构：
[1] Universitat Leipzig,Institut für Medizinische Physik und Biophysik
来源：
BIOCHEMISTRY-MOSCOW | 2004年 / 69卷 / 01期
关键词：
myeloperoxidase; polymorphonuclear leukocytes; reactive oxygen species; hypochlorous acid; luminescence;
D O I：
10.1023/B:BIRY.0000016344.59411.ee
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The heme-containing protein myeloperoxidase is released from stimulated polymorphonuclear leukocytes at sites of inflammation. It is involved in the generation of reactive oxygen and nitrogen species and tissue damage. The general properties and functional aspects of this enzyme are reviewed. Special attention is given to luminescence methods for investigating the release of myeloperoxidase from stimulated cells.
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页码：4 / 9
页数：6
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