The determination of pharmaceutically important ibuprofen by non-aqueous potentiometric titration method

被引：0

作者：

Patil, Vaishali R. ^{[1
]}

Deohate, Pradip P. ^{[1
]}

机构：

[1] Shri Radhakisan Laxminarayan Toshniwal Coll Sci, Dept Chem, Akola 444001, Maharashtra, India

来源：

JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2013年 / 90卷 / 09期

关键词：

Ibuprofen; non-aqueous; potentiometric titration;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The determination of pharmaceutically important ibuprofen by non-aqueous potentiometric titration method using isopropyl alcohol as the solvent and KOH in isopropyl alcohol as the titrant has been established. The study of effect of solvent and concentration on potentiometric determination of ibuprofen has been carried out followed by the estimation of ibuprofen in single component tablets. The titrations were carried out using a pair of glass and calomel electrode. The method was found to be precise for assay of ibuprofen and results obtained are comparable with those obtained by I.P. method.

引用

页码：1379 / 1382

页数：4

共 18 条

[1]

[Anonymous], 2004, BRIT PHARMACOPOEIA, VII

[2]

[Anonymous], 2004, BRIT PHARMACOPOEIA, VI

[3] DETERMINATION OF SOME ANTI-INFLAMMATORY DRUGS IN SERUM BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].