In vitro activity of fosfomycin against extended-spectrum-β-lactamase-producing Escherichia coli and Klebsiella pneumoniae:: Comparison of susceptibility testing procedures

被引：95
作者：
de Cueto, M [1 ]
López, L [1 ]
Hernández, JR [1 ]
Morillo, C [1 ]
Pascual, A [1 ]
机构：
[1] Univ Seville, Hosp Univ Virgen Macarena, Fac Med, Dept Microbiol, Seville 41009, Spain
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 01期
关键词：
D O I：
10.1128/AAC.50.1.368-370.2006
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The agar dilution, broth microdilution, and disk diffusion methods were compared to determine the in vitro susceptibility of 428 extended-spectrum-p-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae to fosfomycin. Fosfomycin showed very high activity against all ESBL-producing strains. Excellent agreement between the three susceptibility methods was found for E. coli, whereas marked discrepancies were observed for K. pneumoniae.
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页码：368 / 370
页数：3
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