Heat-epimerized tea catechins have the same cholesterol-lowering activity as green tea catechins in cholesterol-fed rats

被引:40
|
作者
Kobayashi, M [1 ]
Unno, T
Suzuki, Y
Nozawa, A
Sagesaka, Y
Kakuda, T
Ikeda, I
机构
[1] Ito En Ltd, Cent Res Inst, Shizuoka 4210516, Japan
[2] Tohoku Univ, Grad Sch Agr Sci, Dept Food Funct & Hlth, Lab Food & Biomol Sci, Sendai, Miyagi 9818555, Japan
关键词
tea catechins; heat-epimerized tea catechins; cholesterol; rats;
D O I
10.1271/bbb.69.2455
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Tea catechins are known to be epimerized by heat treatment. The effect of heat-epimerized tea catechins on serum cholesterol concentration was compared with that of green tea catechins. Our observations strongly suggest that both tea catechins and heat-epimerized tea catechins lower serum cholesterol concentration by inhibiting cholesterol absorption in the intestine. There was no differential effect between the two catechin preparations.
引用
收藏
页码:2455 / 2458
页数:4
相关论文
共 33 条
  • [21] Green tea extract attenuates non alcoholic fatty liver disease by decreasing hyperlipidemia and enhancing Superoxide dismutase activity in cholesterol-fed rats
    Labdi, Aicha
    Amiali, Malek
    Bachir, Yacine Nait
    Merouane, Abdelaziz
    Dahman-Zouambi, Amina
    Koceir, Elhadj Ahmed
    Bitam, Arezki
    MEDITERRANEAN JOURNAL OF NUTRITION AND METABOLISM, 2018, 11 (03) : 295 - 306
  • [22] Green tea catechins (EGCG and EGC) have modulating effects on the activity of doxorubicin in drug-resistant cell lines
    Stammler, G
    Volm, M
    ANTI-CANCER DRUGS, 1997, 8 (03) : 265 - 268
  • [23] Green tea extract influnces plasma and liver cholesterol in rats fed hypercholesterolemic diet.
    Oh, JH
    Kim, JL
    Kin, KI
    Kang, JS
    FASEB JOURNAL, 2004, 18 (04): : A524 - A524
  • [24] Cholesterol-lowering and antioxidant status-improving efficacy of germinated giant embryonic rice (Oryza sativa L.) in high cholesterol-fed rats
    Lee, Yeon Ri
    Kim, Chae Eun
    Kang, Mi Young
    Nam, Seok Hyun
    ANNALS OF NUTRITION AND METABOLISM, 2007, 51 (06) : 519 - 526
  • [25] The hypocholesterolemic effect of green tea catechin, (-)-epigallocatechin gallate via upregulation of hepatic cholesterol 7 alpha-hydroxylsae (CYP7A1) in cholesterol-fed rat
    Lee, Mak-Soon
    Kim, Yangha
    FASEB JOURNAL, 2008, 22
  • [26] Black and green tea improves lipid profile and lipid peroxidation parameters in Wistar rats fed a high-cholesterol diet
    Alshatwi, Ali A.
    Al Obaaid, Manal A.
    Al Sedairy, Sahar A.
    Ramesh, Elango
    Lei, Kai Y.
    JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2011, 67 (01) : 95 - 104
  • [27] Black and green tea improves lipid profile and lipid peroxidation parameters in Wistar rats fed a high-cholesterol diet
    Ali A. Alshatwi
    Manal A. Al Obaaid
    Sahar A. Al Sedairy
    Elango Ramesh
    Kai Y. Lei
    Journal of Physiology and Biochemistry, 2011, 67 : 95 - 104
  • [28] Catechin-rich green tea extract increases serum cholesterol levels in normal diet- and high fat diet-fed rats
    Toshikazu Suzuki
    Ayumi Takagi
    Michiyo Takahashi
    BMC Proceedings, 6 (Suppl 3)
  • [29] A fermented mixed tea made with camellia (Camellia japonica) and third-crop green tea leaves prevents nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet
    Omagari, Katsuhisa
    Suruga, Kazuhito
    Kyogoku, Akira
    Nakamura, Satomi
    Sakamoto, Ai
    Nishioka, Shinta
    Ichimura, Mayuko
    Miyata, Yuji
    Tajima, Koichi
    Tsuneyama, Koichi
    Tanaka, Kazunari
    HEPATOBILIARY SURGERY AND NUTRITION, 2018, 7 (03) : 175 - +
  • [30] Catechin-rich green tea extract increases the expression of genes of the cholesterol synthetic pathways in livers of normal diet- and high-fat diet-fed rats
    Toshikazu Suzuki
    Mayumi Nagata
    Ayumi Takagi
    Cancer & Metabolism, 2 (Suppl 1)