Heat-epimerized tea catechins have the same cholesterol-lowering activity as green tea catechins in cholesterol-fed rats

被引:40
|
作者
Kobayashi, M [1 ]
Unno, T
Suzuki, Y
Nozawa, A
Sagesaka, Y
Kakuda, T
Ikeda, I
机构
[1] Ito En Ltd, Cent Res Inst, Shizuoka 4210516, Japan
[2] Tohoku Univ, Grad Sch Agr Sci, Dept Food Funct & Hlth, Lab Food & Biomol Sci, Sendai, Miyagi 9818555, Japan
关键词
tea catechins; heat-epimerized tea catechins; cholesterol; rats;
D O I
10.1271/bbb.69.2455
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Tea catechins are known to be epimerized by heat treatment. The effect of heat-epimerized tea catechins on serum cholesterol concentration was compared with that of green tea catechins. Our observations strongly suggest that both tea catechins and heat-epimerized tea catechins lower serum cholesterol concentration by inhibiting cholesterol absorption in the intestine. There was no differential effect between the two catechin preparations.
引用
收藏
页码:2455 / 2458
页数:4
相关论文
共 33 条
  • [1] EFFECT OF GREEN TEA CATECHINS ON PLASMA-CHOLESTEROL LEVEL IN CHOLESTEROL-FED RATS
    MURAMATSU, K
    FUKUYO, M
    HARA, Y
    JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 1986, 32 (06) : 613 - 622
  • [2] Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate
    Ikeda, I
    Kobayashi, M
    Hamada, T
    Tsuda, K
    Goto, H
    Imaizumi, K
    Nozawa, A
    Sugimoto, A
    Kakuda, T
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2003, 51 (25) : 7303 - 7307
  • [3] Antioxidative activity of green tea polyphenol in cholesterol-fed rats
    Yokozawa, T
    Nakagawa, T
    Kitani, K
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2002, 50 (12) : 3549 - 3552
  • [4] Catechins of green Tea can reduces Cholesterol levels
    不详
    DEUTSCHE ZEITSCHRIFT FUR AKUPUNKTUR, 2012, 55 (02): : 35 - 35
  • [5] Mechanisms of Inhibition of Cholesterol Absorption by Green Tea Catechins
    Kobayashi, Makoto
    Ikeda, Ikuo
    FOOD SCIENCE AND TECHNOLOGY RESEARCH, 2017, 23 (05) : 627 - 636
  • [6] GCG-Rich tea catechins are effective in lowering cholesterol and triglyceride concentrations in hyperlipidemic rats
    Lee, Sang Min
    Kim, Chae Wook
    Kim, Jung Kee
    Shin, Hyun Jung
    Baik, Joo Hyun
    LIPIDS, 2008, 43 (05) : 419 - 429
  • [7] CHOLESTEROL-LOWERING EFFECT OF CLOSTRIDIUM-BUTYRICUM IN CHOLESTEROL-FED RATS
    KOBASHI, K
    TAKEDA, Y
    ITOH, H
    HASE, J
    DIGESTION, 1983, 26 (04) : 173 - 178
  • [8] TEA CATECHINS DECREASE MICELLAR SOLUBILITY AND INTESTINAL-ABSORPTION OF CHOLESTEROL IN RATS
    IKEDA, I
    IMASATO, Y
    SASAKI, E
    NAKAYAMA, M
    NAGAO, H
    TAKEO, T
    YAYABE, E
    SUGANO, M
    BIOCHIMICA ET BIOPHYSICA ACTA, 1992, 1127 (02) : 141 - 146
  • [9] Green tea catechins based functional drink (Green cool) improves the antioxidant status of SD rats fed on high cholesterol and sucrose diets
    Ahmad, Rabia Shabir
    Butt, Masood Sadiq
    Huma, Nuzhat
    Sultan, Muhammad Tauseef
    PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2013, 26 (04) : 721 - 726
  • [10] Effects of green tea catechins on cholesterol and apolipoprotein B production in human hepatocytes.
    Theriault, A
    Yee, W
    Wang, Q
    Agdinaoay, T
    Franke, AA
    Chang, H
    Grandinetti, A
    Adeli, K
    CLINICAL CHEMISTRY, 2000, 46 (06) : A104 - A104