Detection of single gold nanoparticles using spatial modulation spectroscopy implemented with a galvo-scanning mirror system

被引:19
作者
Devadas, Mary Sajini [1 ]
Li, Zhongming [1 ]
Major, Todd A. [1 ]
Lo, Shun Shang [1 ]
Havard, Nicolas [1 ]
Yu, Kuai [1 ]
Johns, Paul [1 ]
Hartland, Gregory V. [1 ]
机构
[1] Univ Notre Dame, Dept Chem & Biochem, Notre Dame, IN 46556 USA
基金
美国国家科学基金会;
关键词
PHOTOTHERMAL CORRELATION SPECTROSCOPY; OPTICAL-ABSORPTION; ROOM-TEMPERATURE; MICROSCOPY DETECTION; PARTICLE MICROSCOPY; PLASMON RESONANCE; SENSITIVITY; LUMINESCENCE; TRACKING; NANORODS;
D O I
10.1364/AO.52.007806
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
The optical extinction of single nanoparticles can be sensitively detected by spatial modulation spectroscopy (SMS), where the particle is moved in and out of a tightly focused laser beam with a piezo-device. Here we show that high sensitivity can be obtained by modulating the beam with a galvo-mirror system, rather than by moving the sample. This work demonstrates an inexpensive method for making a SMS microscope, and shows how an existing laser scanning microscope can be adapted for SMS measurements. The galvo-mirror technique also allows SMS measurements to be performed in a liquid, which is difficult to do with piezo-modulation. (C) 2013 Optical Society of America
引用
收藏
页码:7806 / 7811
页数:6
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