Guiding principles of subcutaneous immunotherapy for allergic rhinitis in Japan

被引：10

作者：

Okamoto, Yoshitaka ^{[1
]}

Ohta, Nobuo ^{[2
]}

Okano, Mitsuhiro ^{[3
]}

Kamijo, Atsushi ^{[4
]}

Gotoh, Minoru ^{[5
]}

Suzuki, Motohiko ^{[6
]}

Takeno, Sachio ^{[7
]}

Terada, Tetsuya ^{[8
]}

Hanazawa, Toyoyuki ^{[1
]}

Horiguchi, Shigetoshi ^{[9
,10
]}

Honda, Kohei ^{[11
]}

Matsune, Shoji ^{[12
]}

Yamada, Takechiyo ^{[13
]}

Yuta, Atsushi ^{[14
]}

Nakayama, Takeo ^{[15
]}

Fujieda, Shigeharu ^{[13
]}

机构：

[1] Chiba Univ, Dept Otorhinolaryngol & Head & Neck Surg, Chiba 2608670, Japan

[2] Yamagata Univ, Dept Otorhinolaryngol & Head & Neck Surg, Yamagata 990, Japan

[3] Okayama Univ, Dept Otorhinolaryngol, Okayama 7008530, Japan

[4] Saitama Med Univ, Dept Otorhinolaryngol Allergy, Moroyama, Saitama, Japan

[5] Nippon Med Sch, Dept Otorhinolaryngol & Head & Neck Surg, Tokyo, Japan

[6] Nagoya City Univ, Dept Otorhinolaryngol & Head & Neck Surg, Nagoya, Aichi, Japan

[7] Hiroshima Univ, Dept Otorhinolaryngol & Head & Neck Surg, Hiroshima 730, Japan

[8] Osaka Med Uinv, Dept Otorhinolaryngol, Osaka, Japan

[9] Iida Hosp, Dept Otorhinolaryngol, Iida, Nagano, Japan

[10] Iida Hosp, Dept Allergol, Iida, Nagano, Japan

[11] Akita Univ, Dept Otorhinolaryngol & Head & Neck Surg, Akita 010, Japan

[12] Nippon Med Sch, Dept Otorhinolaryngol, Musashikosugi Hosp, Tokyo, Japan

[13] Univ Fukui, Dept Otorhinolaryngol & Head & Neck Surg, Fukui, Japan

[14] Yuta Clin, Tsu, Mie, Japan

[15] Kyoto Univ, Dept Hlth Informat, Sch Publ Hlth, Kyoto 6068501, Japan

来源：

AURIS NASUS LARYNX | 2014年 / 41卷 / 01期

关键词：

Allergic rhinitis; Subcutaneous immunotherapy; Principles; Guideline; GRASS-POLLEN IMMUNOTHERAPY; HOUSE-DUST-MITE; DOUBLE-BLIND; CLINICAL-EFFICACY; FOLLOW-UP; ASTHMA; CHILDREN; SENSITIZATIONS; PREVENTION; CELLS;

D O I：

10.1016/j.anl.2013.06.003

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Objective: In anticipation of the development of guidelines for antigen-specific subcutaneous immunotherapy (SCIT), we present recommendations that can serve as guiding principles based on a review of the scientific literature. Methods: Clinical questions (CQs) concerning SCIT were prepared. Literature searches for publications between January 1990 and February 2011 were performed in PubMed, the Cochrane Library, and Japana Centra Revuo Medicina Web version 4. Qualified studies were analyzed and the results were evaluated, consolidated, and codified. Results: We present answers for 13 CQs on the indications, methods, effectiveness and mechanisms of SCIT, with evidence-based recommendations. Conclusion: The guiding principles are intended to be applied to children (<= 15 years old) and adults (>= 16 years old) with allergic rhinitis (AR). These principles can be used by otorhinolaryngologists for diagnosis of AR, evaluation of severity and rhinoscopic findings, performance of antigen challenge tests, and management of systemic anaphylactic reactions associated with SCIT. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

引用

页码：1 / 5

页数：5

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