Synthesis of carboxylactones and new heterocyclic compounds

被引:4
作者
Kochikyan, TV [1 ]
Samvelyan, MA [1 ]
Haroutyunyan, VS [1 ]
Avetissyan, AA [1 ]
机构
[1] Yerevan State Univ, Dept Organ Chem, Yerevan, Armenia
关键词
carboxylactones; esterolactones; Michael addition; thiazolidones;
D O I
10.1080/00397910600591862
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The Michael reaction of 2-ethoxycarbonyl-4-alkoxymethylbutanolides with methyl acrylate affords esterolactones in high yields. Alkaline hydrolysis of the latter resulted in carboxylactones that were transformed into ethyl alpha-bromolactonoesters. The reactions of the latter with thiourea and arylthioureas result in heterocyclic compounds of an original structure joint with a butanolide ring.
引用
收藏
页码:1613 / 1620
页数:8
相关论文
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[3]  
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HAROUTYUNYAN VS, 1994, CHEM J ARMENIA, V47, P91
[5]  
HAROUTYUNYAN VS, 2002, ZH ORG KHIM, V38, P411
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