Contamination of PDMS microchannels by lithographic molds

被引：14

作者：

Bubendorfer, Andrea J. ^{[1
]}

Ingham, Bridget ^{[2
]}

Kennedy, John V. ^{[2
,3
]}

Arnold, W. Mike ^{[1
,2
]}

机构：

[1] Callaghan Innovat Res Ltd, Lower Hutt 5040, New Zealand

[2] MacDiarmid Inst Adv Mat & Nanotechnol, Wellington 6140, New Zealand

[3] GNS Sci, Natl Isotope Ctr, Lower Hutt, New Zealand

来源：

LAB ON A CHIP | 2013年 / 13卷 / 22期

关键词：

ELECTROOSMOTIC FLOW; SURFACE MODIFICATION; CAPILLARY-ELECTROPHORESIS; MICROFLUIDIC SYSTEMS; POLYDIMETHYLSILOXANE; PERFORMANCE; DEVICES; PLASMA;

D O I：

10.1039/c3lc50641j

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

By use of synchrotron X-ray fluorescence and Rutherford backscattering spectrometry, we show the SU-8 soft lithographic process contaminates PDMS. Residues of the antimony containing photoinitiator are transferred from the master mold to the surface of PDMS, uncontrollably intensifying the surface potential, leading to electroosmotic flow variability in PDMS microfluidic devices.

引用

页码：4312 / 4316

页数：5

共 47 条

[1] Disposable Smart lab on a chip for point-of-care clinical diagnostics [J].

Ahn, CH ;

Choi, JW ;

Beaucage, G ;

Nevin, JH ;

Lee, JB ;

Puntambekar, A ;

Lee, JY .

PROCEEDINGS OF THE IEEE, 2004, 92 (01) :154-173

[2]

Aldalali B., 2011, APPL PHYS, V2, P239

[3] Evaluation of polydimethylsiloxane (PDMS) surface modification approaches for microfluidic applications [J].

Almutairi, Zeyad ;

Ren, Carolyn L. ;

Simon, Leonardo .

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2012, 415 :406-412

[4]

Balciunas E., 2012, SPIE REV, V8427, P8427

[5] Electroosmotic flow in poly(dimethylsiloxane) microchannels [J].

Bao, N ;

Xu, JJ ;

Zhang, Q ;

Hang, JL ;

Chen, HY .

JOURNAL OF CHROMATOGRAPHY A, 2005, 1099 (1-2) :203-206

[6] The intrinsic charge on hydrophobic microfluidic substrates [J].

Beattie, James K. .

LAB ON A CHIP, 2006, 6 (11) :1409-1411

[7] Hydrophilization and hydrophobic recovery of PDMS by oxygen plasma and chemical treatment - An SEM investigation [J].

Bodas, Dhananjay ;

Khan-Malek, Chantal .

SENSORS AND ACTUATORS B-CHEMICAL, 2007, 123 (01) :368-373

[8] Microfabrication of PDMS microchannels using SU-8/PMMA moldings and their sealing to polystyrene substrates [J].

Bubendorfer, Andrea ;

Liu, Xianming ;

Ellis, Amanda V. .

SMART MATERIALS AND STRUCTURES, 2007, 16 (02) :367-371

[9]

Choi H, 2004, B KOREAN CHEM SOC, V25, P560

[10] Micropatterning of neural stem cells and Purkinje neurons using a polydimethylsiloxane (PDMS) stencil [J].

Choi, Jin Ho ;

Lee, Hyun ;

Jin, Hee Kyung ;

Bae, Jae-sung ;

Kim, Gyu Man .

LAB ON A CHIP, 2012, 12 (23) :5045-5050

← 1 2 3 4 5 →