Emergence of Pseudomonas aeruginosa with KPC-type carbapenemase in a teaching hospital: an 8-year study

被引：15

作者：

Garcia Ramirez, Dolores ^{[1
]}

Nicola, Federico ^{[1
]}

Zarate, Soledad ^{[1
]}

Relloso, Silvia ^{[1
]}

Smayevsky, Jorgelina ^{[1
]}

Arduino, Sonia ^{[1
]}

机构：

[1] Ctr Med Educ & Clin Res Norberto Quirno CEMIC, Lab Bacteriol Mycol & Parasitol, Buenos Aires, DF, Argentina

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 2013年 / 62卷

关键词：

KLEBSIELLA-PNEUMONIAE; BETA-LACTAMASE; COMPLEX; DISSEMINATION; STRAIN; RESISTANCE; ARGENTINA; GENE;

D O I：

10.1099/jmm.0.059923-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An outbreak of Klebsiella pneumoniae carbapenamase (KPC)-producing K. pneumoniae occurred at our institution. Multiresistant Pseudomonas aeruginosa could have acquired this transmissible resistance mechanism, going unnoticed because its phenotypic detection in this species is difficult. We compared P. aeruginosa isolates obtained before and after the KPC-producing K pneumoniae outbreak. No bla(KPC) genes were detected in the isolates obtained before the outbreak, whereas 33/76 (43 %) of the isolates obtained after the outbreak harboured the bla(KPC) gene. P. aeruginosa may thus become a reservoir of this transmissible resistance mechanism. It is very important to understand the epidemiology of these multiresistant isolates, in order to achieve early implementation of adequate control measures to contain and reduce their dissemination in the hospital environment.

引用

页码：1565 / 1570

页数：6

共 20 条

[1]

Arduino S., 2010, 110 GEN M AM SOC MIC

[2] Expansion of Clonal Complex 258 KPC-2-Producing Klebsiella pneumoniae in Latin American Hospitals: Report of the SENTRY Antimicrobial Surveillance Program [J].