Facile procedures have been developed for the stereoselective synthesis of novel benzo[b] [1,5]oxazepines 4a-f by the condensation reaction between 2-amino phenol 2 and tert-butyl(4R)-2,2-dimethyl-4-(3-oxo-3-phenyl-1-propynyl)-1,3-oxazolane-3-carboxylate 3a-f with MCM-41(H) zeolite in acetonitrile.