A new approach toward the stereoselective synthesis of novel benzo[b][1,5]oxazepines using MCM-41(H) zeolite

被引：0
作者：
Nagarapu, L
Ravirala, N
Rao, NV
机构：
来源：
ENANTIOMER | 2001年 / 6卷 / 06期
关键词：
alpha-acetylenic ketones; 2,3-dihydro-1,5-benzoxazepine enantiomer; efficient procedure; MCM-41 (H) zeolite;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Facile procedures have been developed for the stereoselective synthesis of novel benzo[b] [1,5]oxazepines 4a-f by the condensation reaction between 2-amino phenol 2 and tert-butyl(4R)-2,2-dimethyl-4-(3-oxo-3-phenyl-1-propynyl)-1,3-oxazolane-3-carboxylate 3a-f with MCM-41(H) zeolite in acetonitrile.
引用
收藏
页码：339 / 342
页数：4
相关论文
共 32 条
  • [1] The synthesis of pyrimidin-4-yl substituted α-amino acids.: A versatile approach from alkynyl ketones
    Adlington, RM
    Baldwin, JE
    Catterick, D
    Pritchard, GJ
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1999, (08): : 855 - 866
  • [2] BAURER A, 1974, Patent No. 7702306
  • [3] BEECK JS, 1992, J AM CHEM SOC, V114, P10834
  • [4] Cabarrocas G, 2000, SYNLETT, P595
  • [5] CHAKRABARTI JK, Patent No. 2552403
  • [6] CHIMIRRI A, 1995, ADV HETEROCYCL CHEM, V63, P61
  • [7] Chucholowski A, 1996, CHIMIA, V50, P525
  • [8] AZIDE CYCLIZATIONS WITH ACETYLENIC SILYL KETONE - A GENERAL ACCESS TO FUNCTIONALIZED-1,2,3-TRIAZOLYLACYLSILANE AND ALDEHYDES
    DEGL'INNOCENTI, A
    SCAFATO, P
    CAPPERUCCI, A
    BARTOLETTI, L
    MORDINI, A
    REGINATO, G
    [J]. TETRAHEDRON LETTERS, 1995, 36 (49) : 9031 - 9034
  • [9] BLOOD LEVEL DISTRIBUTION PATTERNS OF DIAZEPAM AND ITS MAJOR METABOLITE IN MAN
    DESILVA, JAF
    KOECHLIN, BA
    BADER, G
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1966, 55 (07) : 692 - &
  • [10] ELKS J, 1990, DICT DRUGS, P291
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