Pulmonary toxoplasmosis in bone marrow transplant recipients: Report of two cases and review

被引：30

作者：

Sing, A

Leitritz, L

Roggenkamp, A

Kolb, HJ

Szabados, A

Fingerle, V

Autenrieth, IB

Heesemann, J

机构：

[1] Univ Munich, Klinikum Grosshadern, Max von Pettenkofer Inst Hyg & Med Mikrobiol, D-8000 Munich, Germany

[2] Univ Munich, Klinikum Grosshadern, Med Klin 3, D-8000 Munich, Germany

来源：

CLINICAL INFECTIOUS DISEASES | 1999年 / 29卷 / 02期

关键词：

D O I：

10.1086/520228

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Toxoplasma gondii may cause disseminated disease in bone marrow transplant (BMT) recipients. Pulmonary toxoplasmosis in BMT patients is rarely described. Mortality rates of >90% have been previously reported. Since pulmonary toxoplasmosis is extremely difficult to diagnose, it is very often detected only at autopsy. Two cases of pulmonary toxoplasmosis in BMT recipients that were diagnosed by visualization of T, gondii tachyzoites in bronchoalveolar lavage fluid and by a new semi-nested PCR method amplifying 18S rRNA from bronchoalveolar lavage fluid are presented, and the literature on pulmonary toxoplasmosis in BMT patients is reviewed.

引用

页码：429 / 433

页数：5

共 27 条

[1]

Beelen D W, 1987, Haematol Blood Transfus, V30, P574

[2]

BEELEN DW, 1986, IMMUN INFEKT, V14, P183

[3] TOXOPLASMA-GONDII PNEUMONIA IN PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME - DIAGNOSIS BY BRONCHOALVEOLAR LAVAGE [J].