Spontaneous spinal epidural haematoma after antiplatelet treatment: a report of two cases

被引:11
作者
Wang, Lushun [1 ]
Liu, Gabriel [1 ]
Subramaniam, Sivashankar [1 ]
Wong, Thomas Aloysius Kah Wai [1 ]
Kumar, Naresh
机构
[1] Natl Univ Singapore Hosp, Dept Orthopaed, Singapore, Singapore
关键词
aspirin; hematoma; epidural; spinal; platelet aggregation inhibitors; spinal cord compression; ticlopidine;
D O I
10.1177/230949901202000326
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
We report 2 cases of spontaneous spinal epidural haematoma after antiplatelet treatment. One patient was on ticlodipine therapy and the other was on aspirin and clopidogrel. Both diagnoses were made using magnetic resonance imaging. One patient underwent multilevel laminectomies and posterior spinal fusion within 24 hours of symptom onset and achieved complete neurological recovery. The other underwent unilateral hemilaminectomies 40 hours after symptom onset and did not show neurological improvement. A high index of suspicion is needed for patients presenting with severe lower back pain and rapid neurological deterioration, especially in those on antiplatelet therapy. Urgent spinal cord decompression and epidural haematoma cord evacuation may provide more favourable outcome.
引用
收藏
页码:386 / 390
页数:5
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