Patterned chemisorption of proteins by thin polymer film dewetting

被引：17
作者：
Lim, Say Kwang [1 ]
Perrier, Sebastien [1 ]
Neto, Chiara [1 ]
机构：
[1] Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia
来源：
SOFT MATTER | 2013年 / 9卷 / 09期
基金：
澳大利亚研究理事会;
关键词：
BIOLOGICAL APPLICATIONS; CROSS-LINKING; SURFACES; GLUTARALDEHYDE; BEHAVIOR; LAYERS;
D O I：
10.1039/c3sm27241a
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The covalent attachment of proteins and their patterning on surfaces are important in the bio-medical industry, for use in applications such as bio-sensing and biocompatible medical devices. In this work, proteins are chemisorbed by reaction of their amine groups to glutaraldehyde- and carboxylic acid-functionalised surfaces, within patterns obtained by the dewetting of thin polystyrene films. The proof of principle is shown that consecutive attachment of proteins within the same pattern is possible using this method.
引用
收藏
页码：2598 / 2602
页数：5
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