Heart failure and development of type 2 diabetes mellitus

被引:0
作者
Antonia Flores-Le-Roux, Juana [1 ,2 ]
Benaiges Boix, David [1 ,2 ]
Pedro-Botet, Juan [1 ,3 ]
机构
[1] Univ Autonoma Barcelona, Dept Med, E-08193 Barcelona, Spain
[2] Hosp del Mar, Serv Endocrinol, Barcelona, Spain
[3] Hosp del Mar, Med Interna Serv, Barcelona, Spain
来源
MEDICINA CLINICA | 2012年 / 138卷 / 13期
关键词
Heart failure; Diabetes; Insulin resistance; LEFT-VENTRICULAR DYSFUNCTION; INSULIN-POTASSIUM INFUSION; SKELETAL-MUSCLE; BLOOD-PRESSURE; RISK-FACTORS; DOUBLE-BLIND; FIBER-TYPE; BODY-MASS; RESISTANCE; GLUCOSE;
D O I
10.1016/j.medcli.2011.07.019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure and diabetes are chronic conditions that frequently concur in the same patient. DM2 is a known risk factor for the development of heart failure and is related with a worse outcome. Some studies have found that heart failure is also associated with a greater incidence of diabetes. This relationship has been less studied and the mechanisms underneath this association are not fully understood. We have done a review of the literature in search for studies that evaluate the relationship between heart failure, insulin resistance and the development of type 2 diabetes, as well as the possible mechanisms leading to this situation, such as sympathetic hyperactivation, increased concentration of free fatty acids and adiponectin resistance. (C) 2010 Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码:579 / 583
页数:5
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