Algorithm for Total Face and Multiorgan Procurement From a Brain-Dead Donor

被引:18
作者
Brazio, P. S. [1 ]
Barth, R. N. [2 ]
Bojovic, B. [3 ]
Dorafshar, A. H. [3 ]
Garcia, J. P. [4 ]
Brown, E. N. [3 ]
Bartlett, S. T. [2 ]
Rodriguez, E. D. [3 ]
机构
[1] Univ Maryland, Sch Med, Dept Surg, Baltimore, MD 21201 USA
[2] Univ Maryland, Sch Med, Div Transplantat, Baltimore, MD 21201 USA
[3] R Adams Cowley Shock Trauma Ctr, Div Plast Surg, Baltimore, MD USA
[4] Univ Maryland, Sch Med, Div Cardiac Surg, Baltimore, MD 21201 USA
关键词
Composite tissue transplantation; face transplantation; multiorgan donor; organ and tissue procurement; organ protection and preservation; organ sharing; COMPOSITE TISSUE-TRANSPLANTATION; GRAFT PROCUREMENT; ALLOGRAFT; OPERATION; RECOVERY; MODEL; HAND;
D O I
10.1111/ajt.12382
中图分类号
R61 [外科手术学];
学科分类号
摘要
Procurement of a facial vascularized composite allograft (VCA) should allow concurrent procurement of all solid organs and ensure their integrity. Because full facial procurement is time-intensive, simultaneous-start procurement could entail VCA ischemia over 12h. We procured a total face osteomyocutaneous VCA from a brain-dead donor. Bedside tracheostomy and facial mask impression were performed preoperative day 1. Solid organ recovery included heart, lungs, liver, kidneys, and pancreas. Facial dissection time was 12h over 15h to diminish ischemia while awaiting recipient preparation. Solid organ recovery began at 13.5h, during midfacial osteotomies, and concluded immediately after facial explantation. Facial thoracic and abdominal teams worked concurrently. Estimated blood loss was 1300mL, requiring five units of pRBC and two units FFP. Urine output, MAP, pH and PaO2 remained normal. All organs had good postoperative function. We propose an algorithm that allows face first, concurrent completion recovery of a complex facial VCA by planning multiple pathways to expedient recovery of vital organs in the event of clinical instability. Beginning the recipient operation earlier may reduce waiting time due to extensive recipient scarring causing difficult dissection.
引用
收藏
页码:2743 / 2749
页数:7
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