Diagnosis and multimodal therapy for extragastrointestinal stromal tumor of the prostate: A case report

被引：13

作者：

Ou, Zhenyu ^{[1
]}

Cao, Zhenzhen ^{[2
]}

He, Yao ^{[1
]}

Tang, Dihong ^{[2
]}

机构：

[1] Cent S Univ, Dept Urol, Xiangya Hosp, Changsha 410008, Hunan, Peoples R China

[2] Cent S Univ, Dept Gynecol Oncol, Affiliated Tumor Hosp, Xiangya Med Sch, Changsha 410013, Hunan, Peoples R China

来源：

EXPERIMENTAL AND THERAPEUTIC MEDICINE | 2013年 / 6卷 / 02期

关键词：

extragastrointestinal stromal tumors; prostate; diagnosis; targeted therapy; EFFICACY; SAFETY;

D O I：

10.3892/etm.2013.1156

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Extragastrointestinal stromal tumors (EGISTs), which are neoplasms outside the digestive tract, are predominantly observed in the greater omentum and retroperitoneum. The clinicopathological and molecular characteristics of EGISTs are similar to those of gastrointestinal stromal tumors (GISTs). EGISTs originating from the prostate are extremely rare. In this study, we report a case of a prostatic EGIST in a 39-year-old male, who presented with frequency, urgency, dysuria and a prostatic mass. A 10-core transrectal ultrasound-guided prostate biopsy was performed, and the histological and immunohistochemical results confirmed the diagnosis of EGIST. The patient received a radical prostatectomy, followed by targeted therapy with imatinib (400 mg, daily) for 1 year. Neither recurrence nor metastasis was detected at a 24-month follow-up.

引用

页码：378 / 380

页数：3

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