A cost-sensitive rotation forest algorithm for gene expression data classification

被引:53
作者
Lu, Huijuan [1 ]
Yang, Lei [1 ]
Yan, Ke [1 ]
Xue, Yu [2 ]
Gao, Zhigang [3 ]
机构
[1] China Jiliang Univ, Coll Informat Engn, 258 Xueyuan St, Hangzhou 310018, Zhejiang, Peoples R China
[2] Nanjing Univ Informat Sci & Technol, Nanjing 210044, Jiangsu, Peoples R China
[3] Hangzhou Dianzi Univ, Coll Comp Sci, Hangzhou 310018, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
Gene expression data; Rotation forest; Cost-sensitive; Misclassification cost; Rejection cost; Test cost; EXTREME LEARNING-MACHINE; ENSEMBLE; FRAMEWORK; SELECTION; REGRESSION; DIAGNOSIS; MODEL;
D O I
10.1016/j.neucom.2016.09.077
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Existing works show that the rotation forest algorithm has competitive performance in terms of classification accuracy for gene expression data. However, most existing works only focus on the classification accuracy and neglect the classification costs. In this study, we propose a cost-sensitive rotation forest algorithm for gene expression data classification. Three classification costs, namely misclassification cost, test cost and rejection cost, are embedded into the rotation forest algorithm. This extension of the rotation forest algorithm is named as cost-sensitive rotation forest algorithm. Experimental results show that the cost-sensitive rotation forest algorithms effectively reduce the classification cost and make the classification result more reliable.
引用
收藏
页码:270 / 276
页数:7
相关论文
共 46 条
[1]   Gene expression data analysis [J].
Brazma, A ;
Vilo, J .
FEBS LETTERS, 2000, 480 (01) :17-24
[2]   Random forests [J].
Breiman, L .
MACHINE LEARNING, 2001, 45 (01) :5-32
[3]   Random forests [J].
Breiman, L .
MACHINE LEARNING, 2001, 45 (01) :5-32
[4]  
Dadye Harold Buko, 2013, International Journal of Digital Content Technology and its Applications, V7, P939, DOI 10.4156/jdcta.vol7.issue7.111
[5]  
Demir Cigdem, 2005, TECH REP
[6]   Predicting Hub Genes Associated with Cervical Cancer through Gene Co-Expression Networks [J].
Deng, Su-Ping ;
Zhu, Lin ;
Huang, De-Shuang .
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2016, 13 (01) :27-35
[7]   Mining the bladder cancer-associated genes by an integrated strategy for the construction and analysis of differential co-expression networks [J].
Deng, Su-Ping ;
Zhu, Lin ;
Huang, De-Shuang .
BMC GENOMICS, 2015, 16
[8]  
Feng S., 2015, COST SENSITIVE DECIS
[9]   A Cost Sensitive Minimal Learning Machine for Pattern Classification [J].
Gomes, Joao Paulo P. ;
Souza, Amauri H., Jr. ;
Corona, Francesco ;
Rocha Neto, Ajalmar R. .
NEURAL INFORMATION PROCESSING, PT I, 2015, 9489 :557-564
[10]  
Hosseinzadeh M, 2015, 2015 INTERNATIONAL SYMPOSIUM ON ARTIFICIAL INTELLIGENCE AND SIGNAL PROCESSING (AISP), P35, DOI 10.1109/AISP.2015.7123535