Bacillus cereus Necrotizing Pneumonia in a Patient with Nephrotic Syndrome

被引：14

作者：

Miyata, Jun ^{[1
]}

Tasaka, Sadatomo ^{[1
]}

Miyazaki, Masaki ^{[1
]}

Yoshida, Syuichi ^{[1
]}

Naoki, Katsuhiko ^{[1
]}

Sayama, Koichi ^{[1
]}

Asano, Koichiro ^{[1
]}

Fujiwara, Hiroshi ^{[2
]}

Ohkusu, Kiyofumi ^{[3
]}

Hasegawa, Naoki ^{[2
]}

Betsuyaku, Tomoko ^{[1
]}

机构：

[1] Keio Univ, Sch Med, Dept Med, Div Pulm Med, Tokyo 108, Japan

[2] Keio Univ, Sch Med, Ctr Infect Dis & Infect Control, Tokyo 108, Japan

[3] Gifu Univ, Grad Sch Med, Dept Microbiol Regenerat & Adv Med Sci, Gifu, Japan

来源：

INTERNAL MEDICINE | 2013年 / 52卷 / 01期

关键词：

Bacillus cereus; necrotizing pneumonia; nephrotic syndrome; corticosteroid; hypogammaglobulinemia; FATAL PNEUMONIA; BACTEREMIA; INFECTION; ANTHRACIS; LEUKEMIA;

D O I：

10.2169/internalmedicine.52.7282

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Bacillus cereus (B. cereus) is a Gram-positive rod that is widely distributed in the environment and can be a cause of food poisoning. We herein present a case of B. cereus necrotizing pneumonia in a patient with nephrotic syndrome under corticosteroid treatment after developing transient gastroenteritis symptoms. B. cereus was isolated from bronchial lavage fluid and transbronchial biopsy specimens. A multiplex polymerase chain reaction analysis of the toxin genes revealed a strain possessing enterotoxicity. The patient recovered after one week of intravenous meropenem followed by a combination of oral moxifloxacin and clindamycin. B. cereus is a pathogen that causes necrotizing pneumonia in immunocompromised hosts.

引用

页码：101 / 104

页数：4

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