Oleuropein: A Valuable Bio-Renewable Synthetic Building Block

被引：17
作者：
Cavaca, Lidia A. S. [1 ]
Afonso, Carlos A. M. [1 ]
机构：
[1] Univ Lisbon, Res Inst Med IMed ULisboa, Fac Pharm, Ave Prof Gama Pinto, P-1649003 Lisbon, Portugal
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 2018卷 / 05期
关键词：
Natural products; Green chemistry; Biological activity; Oleuropein; Olive; Elenolic acid; Biomass; Catalysis; OLEA-EUROPAEA L; NATURALLY-OCCURRING IRIDOIDS; ORGANIC-SOLVENT NANOFILTRATION; MICROWAVE-ASSISTED EXTRACTION; OLIVE LEAVES; PHENOLIC-COMPOUNDS; NATURAL-PRODUCTS; SECOIRIDOID GLUCOSIDES; BIOACTIVE DERIVATIVES; ANTIOXIDANT ACTIVITY;
D O I：
10.1002/ejoc.201701136
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The isolation and structural elucidation of key active compounds from natural sources have grown increasingly in importance, and oleuropein has come to be seen as a potentially valuable natural compound for employment as a starting material for the generation of new compounds with new therapeutic utility. This microreview focuses on the synthetic transformations of oleuropein, together with its structure elucidation and isolation, biosynthesis, biodegradation, and biological properties.
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收藏
页码：581 / 589
页数：9
相关论文
共 108 条
[1]   Olive Tree (Olea europeae L.) Leaves: Importance and Advances in the Analysis of Phenolic Compounds [J].
Abaza, Leila ;
Taamalli, Amani ;
Nsir, Houda ;
Zarrouk, Mokhtar .
ANTIOXIDANTS, 2015, 4 (04) :682-698
[2]   Oleuropein prevents ethanol-induced gastric ulcers via elevation of antioxidant enzyme activities in rats [J].
Alirezaei, Masoud ;
Dezfoulian, Omid ;
Neamati, Shima ;
Rashidipour, Marzyeh ;
Tanideh, Nader ;
Kheradmand, Arash .
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2012, 68 (04) :583-592
[3]   ACCUMULATION OF OLEUROPEIN DERIVATIVES DURING OLIVE MATURATION [J].
AMIOT, MJ ;
FLEURIET, A ;
MACHEIX, JJ .
PHYTOCHEMISTRY, 1989, 28 (01) :67-69
[4]   RP-HPLC-DAD-ESI-QTOF-MS based metabolic profiling of the potential Olea europaea by-product "wood" and its comparison with leaf counterpart [J].
Ammar, Sonda ;
del Mar Contreras, Maria ;
Gargouri, Boutheina ;
Segura-Carretero, Antonio ;
Bouaziz, Mohamed .
PHYTOCHEMICAL ANALYSIS, 2017, 28 (03) :217-229
[5]   Rapid quantitative determination of oleuropein in olive leaves (Olea europaea) using mid-infrared spectroscopy combined with chemometric analyses [J].
Aouidi, Fathia ;
Dupuy, Nathalie ;
Artaud, Jacques ;
Roussos, Sevastianos ;
Msallem, Monji ;
Gaime, Isabelle Perraud ;
Hamdi, Moktar .
INDUSTRIAL CROPS AND PRODUCTS, 2012, 37 (01) :292-297
[6]   Optimisation and comparative kinetics study of polyphenol extraction from olive leaves (Olea europaea) using heated water/glycerol mixtures [J].
Apostolakis, Alexandros ;
Grigorakis, Spyros ;
Makris, Dimitris P. .
SEPARATION AND PURIFICATION TECHNOLOGY, 2014, 128 :89-95
[7]   Effect of convective solar drying on colour, total phenols and radical scavenging activity of olive leaves (Olea europaea L.) [J].
Bahloul, Neila ;
Boudhrioua, Nourhene ;
Kouhila, Mohammed ;
Kechaou, Nabil .
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 2009, 44 (12) :2561-2567
[8]   Adsorption of olive leaf (Olea europaea L.) antioxidants on silk fibroin [J].
Baycin, Deniz ;
Altiok, Evren ;
Ulku, Semra ;
Bayraktar, Oguz .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2007, 55 (04) :1227-1236
[9]   Acid rearrangement of secoiridoids related to oleuropein and secologanin [J].
Bianco, A ;
Jensen, SR ;
Olesen, J ;
Passacantilli, P ;
Ramunno, A .
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2003, 2003 (22) :4349-4354
[10]   Effects of geographical origin and extraction methods on total phenolic yield of olive tree (Olea europaea) leaves [J].
Bilgin, Mehmet ;
Sahin, Selin .
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS, 2013, 44 (01) :8-12
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