Photoelectrochemical C-H Alkylation of Heteroarenes with Organotrifluoroborates

被引：232

作者：

Yan, Hong ^{[1
]}

Hou, Zhong-Wei ^{[1
]}

Xu, Hai-Chao ^{[1
]}

机构：

[1] Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 14期

基金：

中国博士后科学基金;

关键词：

C-H alkylation; electrochemistry; oxidation; photoelectrochemistry; radical reactions; ELECTROCHEMICAL OXIDATION; PHOTOREDOX CATALYSIS; ORGANIC-MOLECULES; CARBOXYLIC-ACIDS; RADICALS; GENERATION; FUNCTIONALIZATION; POTENTIALS; STRATEGIES; SYSTEM;

D O I：

10.1002/anie.201814488

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A photoelectrochemical method for the C-H alkylation of heteroarenes with organotrifluoroborates has been developed. The merger of electrocatalysis and photoredox catalysis provides a chemical oxidant-free approach for the generation and functionalization of alkyl radicals from organotrifluoroborates. A variety of heteroarenes were functionalized using primary, secondary, and tertiary alkyltrifluoroborates with excellent regio- and chemoselectivity.

引用

收藏

页码：4592 / 4595

页数：4

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