Functionalized 1,4-Benzothiazine: A Versatile Scaffold with Diverse Biological Properties

被引：29
作者：
Ajani, Olayinka Oyewale [1 ]
机构：
[1] Covenant Univ, Dept Chem, Sch Nat & Appl Sci, Coll Sci & Technol, Ota, Ogun State, Nigeria
来源：
ARCHIV DER PHARMAZIE | 2012年 / 345卷 / 11期
关键词：
1,4-Benzothiazine; Aminothiophenol; Antibacterial activity; Wide spectrum; THIAZA POLYCYCLIC COMPOUNDS; POTENTIALLY BIOACTIVE AZA; BRIDGEHEAD NITROGEN ATOM; ANTIMICROBIAL ACTIVITY; STAPHYLOCOCCUS-AUREUS; HEPATITIS-C; MICROBIOLOGICAL EVALUATION; SULFONE DERIVATIVES; SEMOTIADIL FUMARATE; CALCIUM-ANTAGONIST;
D O I：
10.1002/ardp.201200140
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
1,4-Benzothiazines are known to represent a class of medicinally important heterocyclic compounds which are extensively used in drug design. They have wide biological properties which qualify them as excellent scaffolds in therapeutic and medicinal research. Thus, many derivatives of this compound have been synthesized as target structures in novel drug development. Hence, the motivation for this present review was the known widespread application of the 1,4-benzothiazine scaffolds.
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页码：841 / 851
页数：11
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