A Novel Type of Highly Effective Nonionic Gemini Alkyl O-Glucoside Surfactants: A Versatile Strategy of Design

被引:52
|
作者
Liu, Songbai [1 ]
Sang, Ruocheng [1 ]
Hong, Shan [1 ]
Cai, Yujing [1 ]
Wang, Hua [2 ]
机构
[1] Zhejiang Univ, Fuli Inst Food Sci, Dept Food Sci & Nutr, Hangzhou 310058, Zhejiang, Peoples R China
[2] Zhejiang Univ, Ctr Anal & Measurement, Hangzhou 310058, Zhejiang, Peoples R China
基金
中央高校基本科研业务费专项资金资助;
关键词
AGGREGATION PROPERTIES; ADSORPTION; PH;
D O I
10.1021/la401569n
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel type of highly effective gemini alkyl glucosides has, been rationally designed and synthesized The gemini surfactants have been readily prepared. by glycosylation of the gemini alkyl chains that are synthesized with regioselective ring-opening of ethylene glycol epoxides by the alkyl alcohols. The new gemini alkyl glucosides exhibit significantly better surface activity than the known results. Then rheological, DLS, and TEM studies have revealed the intriguing self-assembly behavior of the novel gemini surfactants. This study has proved the effectiveness of the design of gemini alkyl glucosides which is modular, extendable, and synthetically simple. The new gemini surfactants have great potential as nano carriers in drug and gene delivery.
引用
收藏
页码:8511 / 8516
页数:6
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